Sort   by:  
 Page size 
UnknownRegulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses.
Not available
S-EPMC4826619 | biostudies-literature
ProteomicsHepatocyte Deletion of Triglyceride-Synthesis Enzyme DGAT2 Reduces Steatosis without Increasing Inflammation or Fibrosis
Non-alcoholic fatty liver disease (NAFLD) is characterized by excess lipid accumulation in hepatocytes and reprepresents a huge public health problem owing to its propensity to progress to non-alcoholic steatohepatitis (NASH), fibrosis, and liver failure. The lipids stored in hepatic steatosis are p...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-26 | PXD013423 | Pride
Triacylglycerol Liver Diacylglycerol Nonalcoholic fatty liver disease Steatohepatitis Dietary lipids 
ProteomicsInhibiting sphingolipid synthesis improves outcomes and survival in GARP-mutant wobbler mouse, an ALS model
Defects of the endosomal and lysosomal systems have been increasingly linked to adult neurodegenerative diseases1,2. Deficiencies in the retrograde trafficking pathway between endosomes and the Golgi apparatus lead to forms of Alzheimer’s and Parkinson’s diseases in the case of retromer mutations, o...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD007981 | Pride
Lc-msms Silac Mef 
UnknownA GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells.
Not available
S-EPMC8752777 | biostudies-literature
UnknownInhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration.
Not available
S-EPMC7229683 | biostudies-literature
ProteomicsBRG1 loss predisposes lung cancers to replicative stress and ATR dependency
Gupta M, Concepcion CP, Fahey CG, Keshishian H, Bhutkar A, Brainson CF, Sanchez-Rivera FJ, Pessina P, Kim JY, Simoneau A, Paschini M, Beytagh MC, Stanclift C, Schenone M, Mani DR, Li C, Oh A, Li F, Hu H, Karatza A, Bronson RT, Shaw AT, Hata AN, Wong K, Zou L, Carr SA, Jacks T, Kim CF. Cancer Res 20...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-07-08 | MSV000085701 | MassIVE
Unknownγδ T Cells Contribute to Injury in the Developing Brain.
Not available
S-EPMC5840494 | biostudies-literature
TranscriptomicsNuclear Factor I/B is an Oncogene in Small Cell Lung Cancer
Small cell lung cancer (SCLC) is an aggressive cancer often diagnosed only after it has metastasized to distant sites (Meuwissen and Berns 2005; Cooper and Spiro 2006). Despite the need to better understand this disease, SCLC remains poorly characterized at the molecular and genomic levels (Forgacs ...
ORGANISM(S): Mus musculus 
2011-12-08 | E-GEOD-29533 | biostudies-arrayexpress
UnknownImpaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans.
Not available
S-EPMC3069776 | biostudies-literature
ProteomicsProteomics/phosphoproteomics of human iPSC derived lung alveolar epithelial type 2 cells with/without dox-induced activation of oncogenic KRAS G12D
Lung adenocarcinoma is responsible for significant global mortality with limited effective treatments. Although some studies suggest that these tumors arise from alveolar epithelial type 2 cells (AEC2s), there is scant information regarding the early events that might occur in human AEC2s at the inc...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD019240 | Pride
Human Q exactive hf-x 
Sort   by:  
 Page size