Sort   by:  
 Page size 
GenomicsCistromic and epigenomic changes in Prdm16 knock-out brown adipose tissue
Prdm16 is a transcription factor that drives a complete program of brown adipocyte differentiation, but the mechanism by which Prdm16 activates gene transcription remains unknown. Utilizing ChIP-seq teqhnique, we found that Prdm16 binds to chromatin at/near many brown fat-selective genes in BAT. Int...
ORGANISM(S): Mus musculus 
2015-02-10 | E-GEOD-63965 | biostudies-arrayexpress
TranscriptomicsPrdm16 Knockout Brown Adipose Tissue
Gene expression profile from brown adipose tissues of Prdm16 knockout and wile type mice. Prdm16 is a transcription factor that regulates the thermogenic gene program in brown and beige adipocytes. However, whether Prdm16 is required for the development or physiological function of brown adipose ti...
ORGANISM(S): Mus musculus 
2014-04-09 | E-GEOD-55080 | biostudies-arrayexpress
UnknownSpin-orbital Jahn-Teller bipolarons.
Not available
S-EPMC11258125 | biostudies-literature
TranscriptomicsTranscriptome profiling in knock-in mouse models of Huntington's disease [AllelicSeries_6month_TissueSurvey_mRNA]
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that is characterized by motor, cognitive, and psychiatric alterations. The mutation responsible for this disease is an abnormally expanded and unstable CAG repeat within the coding region of the gene encoding huntingtin (...
ORGANISM(S): Mus musculus 
2016-02-15 | E-GEOD-65775 | biostudies-arrayexpress
UnknownProteomic analysis of Medulloblastoma reveals functional biology with translational potential.
Not available
S-EPMC5992829 | biostudies-literature
UnknownEffects of cost surface uncertainty on current density estimates from circuit theory.
Not available
S-EPMC7409782 | biostudies-literature
TranscriptomicsSexual Dimorphic Regulation of Liver Gene Expression by Glucocorticoids
Males and females exhibit differences in the incidence of many major diseases including auto-immune diseases, hepatocellular carcinoma, diabetes, and osteoporosis, which all have important inflammatory components in their etiology. Glucocorticoids are the primary physiological anti-inflammatory horm...
ORGANISM(S): Rattus norvegicus 
2010-10-01 | E-GEOD-13461 | biostudies-arrayexpress
UnknownA systematic review of randomized control trials of HPV self-collection studies among women in sub-Saharan Africa using the RE-AIM framework.
Not available
S-EPMC8672475 | biostudies-literature
TranscriptomicsGene Profiling in Mouse Fetal Ductus Arteriosus
The ductus arteriosus (DA) is a fetal vascular shunt that is located between the main pulmonary artery and the aorta. Oxygenated fetal blood from the placenta is shunted past the uninflated fetal lungs, crosses the DA, and is then available to the peripheral organs. In utero closure of the DA is del...
ORGANISM(S): Mus musculus 
2014-08-05 | E-GEOD-51664 | biostudies-arrayexpress
no omics definedTranscription profiling of rat liver and kidney samples performed in 16 different institutions to determine study factors which are key sources of variability. Raw files available as additional archives.
BACKGROUND: The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variance due to individual, environmental, and technical factors. Meta-analysis of microarray data from untreated or vehicle-treated animals w...
ORGANISM(S): Rattus norvegicus 
2008-10-10 | E-TOXM-39 | biostudies-arrayexpress
Sort   by:  
 Page size