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UnknownThe histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.
Not available
S-EPMC6742567 | biostudies-literature
TranscriptomicsNon-genotoxic Hepatocarcinogens
There is no accurate and well-validated short-term test for non-genotoxic carcinogens, necessitating an expensive two year rodent bioassay before a risk assessment can begin. We have developed a short-term in vivo rat assay that predicts whether non-genotoxic chemicals are likely to induce hepatic t...
ORGANISM(S): Rattus norvegicus 
2007-06-22 | E-GEOD-8251 | biostudies-arrayexpress
ProteomicsIntegrated liver-secreted and plasma proteomics approaches identify a predictive model that stratifies MASH in bariatric patients
Background & Aims Obesity is a major risk factor for metabolic associated steatotic liver disease (MASLD) which can progress from metabolic associated steatotic liver (MASL) to metabolic associated steatohepatitis (MASH). There are currently no effective and validated screening tools to stratify obe...
ORGANISM(S): Homo sapiens (Human) 
2025-04-14 | PXD052798 | Pride
Masld Hepatokine Apasha Masl Liver-secreted proteome Metabolic associated steatohepatitis Biomarker Plasma proteomics Mash Nash Nafld 
ProteomicsIntegrated liver-secreted and plasma proteomics approaches identify a predictive model that stratifies MASH in bariatric patients
Background & Aims Obesity is a major risk factor for metabolic associated steatotic liver disease (MASLD) which can progress from metabolic associated steatotic liver (MASL) to metabolic associated steatohepatitis (MASH). There are currently no effective and validated screening tools to stratify obe...
ORGANISM(S): Homo sapiens (Human) 
2025-04-14 | PXD052784 | Pride
Masld Hepatokine Apasha Masl Liver-secreted proteome Metabolic associated steatohepatitis Biomarker Plasma proteomics Mash Nash Nafld 
TranscriptomicsLiver Pharmacology and Xenobiotic Response Repertoire
A definition of RNA expression changes that correlate with liver response programs and an understanding of the similarities and differences in responses to different classes of chemicals would aid in new chemical or drug characterization and add to our understanding of liver biology. We have used a ...
ORGANISM(S): Rattus norvegicus 
2008-03-28 | E-GEOD-8858 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium definitive phage type 104 (DT104) isolates
Salmonella enterica serovar Typhimurium (S. Typhimurium) definitive phage type 104 (DT104) has caused significant morbidity and mortality in humans and animals for almost three decades. We have completed the full DNA sequence of one DT104 strain, NCTC13348 and show that the main differences between ...
ORGANISM(S): Salmonella enterica 
2008-09-05 | E-MTAB-20 | biostudies-arrayexpress
UnknownA chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.
Not available
S-EPMC9189931 | biostudies-literature
UnknownRich club analysis in the Alzheimer's disease connectome reveals a relatively undisturbed structural core network.
Not available
S-EPMC4504816 | biostudies-literature
TranscriptomicsTMPRSS2-ERG fusion prostate cancer is a molecularly distinct estrogen-sensitive subclass of aggressive prostate cancer
Common epithelial cancers are believed to become more aggressive through the accumulation of multiple independent molecular events that lead to the deregulation of cell signaling. However, the discovery that the majority of prostate cancers harbor gene fusions of the 5'-untranslated region of androg...
ORGANISM(S): Homo sapiens 
2008-05-27 | E-GEOD-8402 | biostudies-arrayexpress
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
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