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ProteomicsIdentification of receptor-binding domains of Bacteroidales antibacterial pore-forming toxins
Bacteroidales are abundant Gram-negative bacteria present in the gut microbiota of most animals, including humans, where they carry out vital functions for host health. To thrive in this competitive environment, Bacteroidales use sophisticated weapons to outmatch competitors. Among these, BSAPs (Bac...
ORGANISM(S): Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) 
2025-11-29 | PXD062775 | Pride
Lc-msms Bacteroides fragilis Bsap receptor Co-purification Membrane fraction 
UnknownIdentification of receptor-binding domains of Bacteroidales antibacterial pore-forming toxins.
Not available
S-EPMC12853789 | biostudies-literature
GenomicsCistrome of the Aldosterone-activated Mineralocorticoid Receptor in Human Renal Cells
Aldosterone, the main mineralocorticoid hormone in Humans, has a major role in maintaining the hemo-electrolytique homeostasis, by acting in the distal part of nephron. This steroid hormone mainly acts through its binding to a ligand-induced transcription factor, the mineralocorticoid receptor (MR)....
ORGANISM(S): Homo sapiens 
2015-06-12 | E-GEOD-69777 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of chicken Pax5 deficient DT40 B cell line
PAx5 is indispensible for the committment if early lymphoid progenitors to the B cell lineage as well as for the development and maintenance of B cells. To better understand the functional importance of Pax5 in the later stages of B cell development and investigate the targets of Pax5 regulation, w...
ORGANISM(S): Gallus gallus 
2005-04-17 | E-MEXP-270 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice Pax5 targets in B-macrophage bipotential lymphoma cells
B-macrophage bipotential lymphoma cells without Pax5 expression were reconstituted with the Pax5-estrogen receptor fusion protein and changes in transcription profiles in response to 4-hydroxytamoxifen were monitored in vivo
ORGANISM(S): Mus musculus 
2007-09-01 | E-MEXP-1156 | biostudies-arrayexpress
UnknownIdentification of a Fifth Antibacterial Toxin Produced by a Single Bacteroides fragilis Strain.
Not available
S-EPMC6436352 | biostudies-literature
TranscriptomicsWhole genome transcription profile of antigen receptor activated B cells
To search for rapid changes in gene expression following BCR activation, we performed DNA microarray analysis of activated splenic B cells with and without anti-IgM treatment for 3 hour. The expression of a remarkably large set of genes differed significantly. Primary B-lymphocytes were purified fro...
ORGANISM(S): Mus musculus 
2010-05-08 | E-GEOD-15606 | biostudies-arrayexpress
TranscriptomicsThe transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells
Pax5 is a critical regulator of B cell commitment. Here we identified direct Pax5 target genes by streptavidin-mediated ChIP-chip analysis of pro-B cells expressing in vivo biotinylated Pax5. By binding to promoters and enhancers, Pax5 directly regulates the expression of multiple transcription fact...
ORGANISM(S): Mus musculus 
2012-03-29 | E-GEOD-28373 | biostudies-arrayexpress
TranscriptomicsChip-chip from pro-B cells with H3K4me3, H3K4me2 and H3K9ac
The transcription factor Pax5 represses B-lineage-inappropriate genes and activates B-cell-specific genes in B-lymphocytes. Here we have identified 170 novel Pax5-activated genes. Conditional mutagenesis demonstrated that the Pax5-regulated genes require continuous Pax5 activity for normal expressio...
ORGANISM(S): Mus musculus 
2007-08-23 | E-GEOD-8472 | biostudies-arrayexpress
TranscriptomicsChip-chip from pro-B cells with H3K4me3, H3K4me2 and H3K9ac
The transcription factor Pax5 represses B-lineage-inappropriate genes and activates B-cell-specific genes in B-lymphocytes. Here we have identified 170 novel Pax5-activated genes. Conditional mutagenesis demonstrated that the Pax5-regulated genes require continuous Pax5 activity for normal expressio...
ORGANISM(S): Mus musculus 
2010-05-20 | E-GEOD-15145 | biostudies-arrayexpress
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