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Mitochondria share attributes of vesicular transport with their bacterial ancestors given their ability to form mitochondrial-derived vesicles (MDVs). MDV formation enhances with stress and has been explored for its potential role in mitochondrial-directed cellular and extracellular signalling. Alth...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-08 | PXD020110 | Pride
Mouse models of genetic mitochondrial diseases are generally used to understand specific molecular defects and their biochemical consequences, but rarely to map compensatory changes allowing survival. Here we took advantage of the extraordinary mitochondrial resilience of hepatic Lrpprc knockout mic...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD021867 | Pride
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