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ProteomicsProteomic Analysis of Myotube-Secreted Exosomes of Amyotrophic Lateral Sclerosis (ALS) and Healthy subjects
In order to investigate a potential role of muscle exosomes in the pathology of Amyotrophic Lateral Sclerosis (ALS), we undertook a proteomic study of the content of exosomes secreted by myotubes of ALS and Healthy subjects.
ORGANISM(S): Homo sapiens (Human) 
2021-03-25 | PXD015736 | Pride
Muscle Exosome Myotube Motor neuron disease Als Amyotrophic lateral sclerosis 
TranscriptomicsPurified human leukocyte subtype DNA methylation profiles
The objective of the study was to identify differentially methylated regions of DNA (DMRs) that distinguish human leukocyte subtypes, and hence serve as biomarkers for those immune cell types. This file contains Illumina Infinium HumanMethylation27 BeadChip data for human leukocyte subtypes that wer...
ORGANISM(S): Homo sapiens 
2012-11-05 | E-GEOD-39981 | biostudies-arrayexpress
GenomicsMolecular Genetic Studies of Developmental Brain Disorders

Study 1
2R01-NS050375 (PI: DOBYNS, William B.)
The genetic basis of mid-hindbrain malformations
Our general goal for this project is to advance our understanding of human developmental disorders that involve the brainstem and cerebellum - brain structures derived from the embryoni...

phs000455.v1.p1 | EGA
TranscriptomicsEpigenome analysis of aging muscle progenitors
Genome wide DNA methylation profiling of muscle cells extracted from healthy donors at different ages. The Illumina Infinium Human Methylation 450 BeadChip was used to obtain DNA methylation profiles across > 485,000 methylation sites. The muscle cells were extracted from young adults (18-40 years ...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-53302 | biostudies-arrayexpress
UnknownInterferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming.
Not available
S-EPMC9380486 | biostudies-literature
Genomicsena-DATASET-SC-16-09-2014-14:22:12:125-153 - samples
Description not provided
EGAD00001001014 | EGA
Genomicsena-DATASET-SC-16-09-2014-14:25:48:324-154 - samples
Description not provided
EGAD00001001015 | EGA
GenomicsOrigins and functional consequence of somatic mitochondrial DNA mutations
Recent sequencing studies have extensively explored the somatic alterations present in the nuclear genomes of cancers. Although mitochondria control energy metabolism and apoptosis, the origins and impact of cancer-associated mutations in mitochondrial DNA (mtDNA) are unclear. Here, we analysed soma...
EGAS00001000968 | EGA
GenomicsEGAS00001000262-sc-20170314 - samples
Whole Genome Sequencing Illumina HiSeq data from 111 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy (target sequencing depth 50X) with matched blood control (target sequencing depth 30X). This data is from batches 4 to 6.
EGAD00001003225 | EGA
GenomicsThe Natural History of Human Prostate Cancer - samples
Affymetrix SNP6.0 genotype data for prostate cancer patients
EGAD00010000498 | EGA
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