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Cardiac myosin-binding protein C (cMyBP-C) is a thick filament–associated protein that influences actin–myosin interactions. cMyBP-C alters myofilament structure and contractile properties in a protein kinase A (PKA) phosphorylation–dependent manner. To determine the effects of cMyBP-C and its phosp...
ORGANISM(S): Homo sapiens (Human) 
2019-09-26 | PXD015391 | Pride
Gene expression profiling of C2, C1 and C0 iNKT cell subset
We identified a novel subset of iNKT cells, C2 iNKT cells, that circulate in the periphery. Correspondingly, we characterized the tissue-resident iNKT cell subset, C1 iNKT cells. We also found the precursor of these two subsets of iNKT cells, C0 iNKT cells in thymus. The development and terminal mat...
ORGANISM(S): Mus musculus 
2022-08-08 | GSE206627 | GEO
Phosphorylation of cardiac myosin binding protein-C (cMyBP-C) regulates cardiac contraction through modulation of actomyosin interactions mediated by the protein’s amino terminal (N’)-region (C0-C2 domains, 358 amino acids). On the other hand, dephosphorylation of cMyBP-C during myocardial injury re...
ORGANISM(S): Mus musculus 
2021-03-23 | GSE169340 | GEO
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