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ProteomicsGephyrin interactome from mouse brain lysates using anti-gephyrin antibody and anti-gephyrin DARPins
In order to understand the protein interactors of the inhibitory synaptic scaffolding protein gephyrin, we precipitated gephyrin protein complexes from adult mouse brain lysates of both sexes using both a commercial anti-gephyrin antibody (clone 3B11), as well as anti-gephyrin Designed Ankyrin Repea...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-01 | PXD033641 | Pride
Ap-ms Mus musculus 3b11 C56bl/6j mouse Gephyrin Gphn Designed ankyrin repeat domain Darpin Interactome Lc-ms/ms 
Transcriptomicstranscription profiling by array of C57BL/6J mice fed a Western-style diet with or without 0.05% quercetin against mice on a control diet to study the effect of quercetin on obesity and hepatic gene expression
To determine the effect of consumption of a quercetin-rich diet on obesity and dysregulated hepatic gene expression, C56BL/6J mice were fed for 20 weeks on control or a Western diet high in fat, cholesterol and sucrose, both with or without 0.05% quercetin. Chronic dietary intake of quercetin reduce...
ORGANISM(S): Mus musculus 
2012-05-29 | E-GEOD-38141 | biostudies-arrayexpress
TranscriptomicsExpression data from 8-10 week old WT mice maintained in room air or exposed to hyperoxia (FiO2>95%) for 48 hrs
To detect sex-specific differences in gene expression in a model of hyperoxic lung injury in adult C56BL/6J mice. In this dataset, we include the expression data obtained from lungs from 8-10 week old male and female WT C57BL/6J mice exposed to hyperoxia for 48 hours amd room air controls.These data...
ORGANISM(S): Mus musculus 
2014-12-10 | E-GEOD-51039 | biostudies-arrayexpress
TranscriptomicsPancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
A frequently used experimental model of chronic pancreatitis (PC) recapitulating human disease is repeated injection of cerulein to mice. We found that two common substrains of C57BL/6 , C56BL/6J (Jackson) and C57BL/6NHsd (Harlan), exhibit different degree of CP with C57BL/6J beeing more susceptible...
ORGANISM(S): Mus musculus 
2012-10-10 | E-GEOD-41418 | biostudies-arrayexpress
TranscriptomicsM-NM-2-Cryptoxanthin suppresses inflammatory gene expression in diet-induced nonalcoholic steatohepatitis in mice
To evaluate the effect of M-NM-2-cryptoxanthin on diet-induced NASH, we fed a high-cholesterol and high-fat diet (CL diet) with or without 0.003% M-NM-2-cryptoxanthin to C56BL/6J mice for 12 weeks. After feeding, M-NM-2-cryptoxanthin attenuated fat accumulation, increases in Kupffer and activated st...
ORGANISM(S): Mus musculus 
2014-05-28 | E-GEOD-51432 | biostudies-arrayexpress
UnknownMouse genotypes drive the liver and adrenal gland clocks.
Not available
S-EPMC4989183 | biostudies-literature
TranscriptomicsHepatic gene expression in C56BL/6J mice fed a quercetin diet for 20 weeks
Both the 0.05% and 1% querceitn diets did not significantly affect the body weight, fat accumulation, and blood components. However, 0.05% quercetin significantly increased the glutathione/oxidized glutathione ratio in the liver. Moreover, the 1% quercetin diet reduced the lipid peroxidation markers...
ORGANISM(S): Mus musculus 
2015-07-24 | E-GEOD-62805 | biostudies-arrayexpress
UnknownPlacenta-derived extracellular vesicles induce preeclampsia in mouse models.
Not available
S-EPMC7271597 | biostudies-literature
TranscriptomicsCardiac left ventricles of 12 week-old male C57BL/6J and C57BL/6J-chrY mice
We have reported previously that when chromosome Y (chrY) from the mouse strain C57BL/6J (abbreviated as B) was substituted for that of A/J mice (ChrY), cardiomyocytes from the resulting 'chromosome substitution' C57BL/6J-chrY strain (abbreviated as B.Y) were smaller than that of their C57BL/6...
ORGANISM(S): Mus musculus 
2009-05-01 | E-GEOD-15354 | biostudies-arrayexpress
UnknownDifferential expressions of the alternatively spliced variant mRNAs of the µ opioid receptor gene, OPRM1, in brain regions of four inbred mouse strains.
Not available
S-EPMC4208855 | biostudies-literature
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