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ProteomicsTwo circulating biomarkers are associated with the serological status of Rheumatoid Arthritis patients: a tool for precision medicine strategies
In the present work, we aimed to carry out a pipeline based on quantitative proteomics tools to discover, verify and validate circulating proteins that are associated with the presence in serum of RF and ACPA and may therefore have potential for the stratification of RA patients and the application ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037386 | Pride
Rheumatoid anhritis Orosomucoid 1 Multiple reaction monitoring Biomarker Haptoglobin 
ProteomicsA proteomic approach to study Brassica oleracea responses to black rot (Xanthomonas campestris pv. campestris), part 1
Understanding plant’s response mechanisms against pathogenesis is fundamental for the development of resistant crop varieties and more productive agriculture. In this regard, ‘omic’ approaches are heralded as valuable technologies. In this work, combining iTRAQ technology with mass spectrometry, the...
ORGANISM(S): Brassica oleracea var. botrytis (Cauliflower) 
2022-02-23 | PXD009097 | Pride
Proteomics  biotic stress  itraq  mass spectrometry  brassica oleracea  xanthomonas campestris 
ProteomicsA proteomic approach to study Brassica oleracea responses to black rot (Xanthomonas campestris pv. campestris), part 2
Understanding plant’s response mechanisms against pathogenesis is fundamental for the development of resistant crop varieties and more productive agriculture. In this regard, ‘omic’ approaches are heralded as valuable technologies. In this work, combining iTRAQ technology with mass spectrometry, the...
ORGANISM(S): Brassica oleracea var. botrytis (Cauliflower) 
2022-02-23 | PXD009098 | Pride
Proteomics  biotic stress  itraq  mass spectrometry  brassica oleracea  xanthomonas campestris 
ProteomicsAnalysis of endogenous peptides released from osteoarthritic articular cartilage unravels novel pathogenic markers
We have performed a peptidomic strategy to identify endogenous peptides (neopeptides) that are released from knee and/or hip OA cartilage, which may serve as disease markers.
ORGANISM(S): Homo sapiens (Human) 
2019-07-30 | PXD011800 | Pride
Osteoarthritis Cartilage Peptidome 
ProteomicsPREDICTIVE MODELING OF THERAPEUTIC RESPONSE TO CHONDROITIN SULFATE/GLUCOSAMINE HYDROCHLORIDE IN KNEE OSTEOARTHRITIS
In the present study we explored potential protein biomarkers useful to predict the therapeutic response of osteoarthritis (OA) patients treated with pharmaceutical grade Chondroitin sulfate/Glucosamine hydrochloride (CS+GH; Droglican, Bioiberica), in order to optimize therapeutic outcomes.
ORGANISM(S): Homo sapiens (Human) 
2019-09-12 | PXD012444 | Pride
Predictive biomarkers Chondroitin sulfate/glucosamine hydrochloride Proteomics Osteoarthritis 
ProteomicsSulfamethoxazole triggers specific microbial activities under aerobic heterotrophic conditions: A metaproteomic approach
The global sanitary crisis derived from antibiotic multi-resistant bacteria entails the need to reduce sulfamethoxazole (SMX) concentrations in wastewater treatment plants (WWTPs). The key microorganisms and the biotransformation mechanisms leading to SMX removal remain incompletely characterized, p...
ORGANISM(S): environmental samples <b-proteobacteria environmental samples <g-proteobacteria 
2022-09-20 | PXD029711 | Pride
Activated sludge  antibiotics  biotransformation  enzymes  micropollutants  proteome  transformation products  wastewater 
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