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Centrosome-enriched fractions of Jurkat E6-1 human T cells (JK), human embryonic kidney (HEK) 293 cells, resting human T lymphoblasts (LT CTRL) and activated human T lymphoblasts (LT ACT), with one biological replicate for each condition, were analysed by label-free LC-MS/MS. For further details, re...
ORGANISM(S): Homo sapiens (Human) 
2025-12-18 | PXD063199 | Pride
Human resting and activated T lymphoblast (LT CTRL and LT ACT) centrosome-enriched subcellular fractions from LT CTRL and LT ACT were prepared as analysed by multiplexed quantitative proteomics and LC-MS/MS. Samples from different donors were pooled after first lysis. For further details, refer to r...
ORGANISM(S): Homo sapiens (Human) 
2025-12-18 | PXD063195 | Pride
Specialized tissues demand support for long-term fitness. In the heart, for example, the removal of spent mitochondria by macrophages is critical for cardiac function. In an organismal-wide screening, we show here that the transfer of mitochondria to macrophages is prominent in other organs that rel...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-02 | PXD053573 | Pride
Embryonic stem cells (ESCs) can be maintained in the naïve state through inhibition of Mek1/2 and Gsk3 (2i). A relevant effect of 2i is the inhibition of Cdk8/19, which are negative regulators of the Mediator complex, responsible for the activity of enhancers. Inhibition of Cdk8/19 (Cdk8/19i) stimul...
2021-02-10 | MTBLS301 | MetaboLights
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