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TranscriptomicsAMPK governs lineage specification through Tfeb-dependent regulation of lysosomes
Faithful execution of developmental programs relies on the acquisition of unique cell identities from pluripotent progenitors, a process governed by combinatorial inputs from numerous signaling cascades that ultimately dictate lineage-specific transcriptional outputs. Despite growing evidence that m...
ORGANISM(S): Mus musculus 
2016-03-09 | E-GEOD-77705 | biostudies-arrayexpress
UnknownBasolateral amygdala activation enhances object recognition memory by inhibiting anterior insular cortex activity.
Not available
S-EPMC9295787 | biostudies-literature
TranscriptomicsTranscription profiling of murine livers after resveratrol treatment of mice on a high-calorie diet
Resveratrol (3,5,4'-trihydroxystilbene) extends the lifespan of diverse species including yeast, worms, and flies. In these organisms, lifespan extension is dependent on Sir2, a conserved deacetylase proposed to underlie the beneficial effects of caloric restriction (CR). Here we show that resveratr...
ORGANISM(S): Mus musculus 
2008-06-21 | E-GEOD-6089 | biostudies-arrayexpress
TranscriptomicsCREB ChIP-chip and HaloCHIP-chip experiments
Regulation of gene expression is essential for normal development and cellular growth. Transcriptional events are tightly controlled both spatially and temporally by specific DNA-protein interactions. In this study we finely map the genome-wide targets of the CREB protein across all known and predi...
ORGANISM(S): Homo sapiens 
2010-05-22 | E-GEOD-18347 | biostudies-arrayexpress
UnknownFacilitators and barriers to successful recruitment into a large comparative effectiveness trial: a qualitative study.
Not available
S-EPMC7333580 | biostudies-literature
UnknownOptimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight.
Not available
S-EPMC7171946 | biostudies-literature
UnknownRationale and design of the glycemia reduction approaches in diabetes: a comparative effectiveness study (GRADE).
Not available
S-EPMC3714493 | biostudies-literature
UnknownAssociation of Baseline Factors With Glycemic Outcomes in GRADE: A Comparative Effectiveness Randomized Clinical Trial.
Not available
S-EPMC10973909 | biostudies-literature
UnknownMedication Adherence in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).
Not available
S-EPMC12824802 | biostudies-literature
UnknownAssociation of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort.
Not available
S-EPMC7818323 | biostudies-literature
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