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MetabolomicsThe Cancer-Associated Microbe Library reveals functional host-microbe interactions during colorectal cancer progression

Functional characterization of microbes which colonize CRC is impeded by a lack of bacterial strains from tumor tissues. Here, we report the Cancer-Associated Microbe Library (CAM-L), comprising more than 3,000 viable bacterial isolates, representing 121 distinct species, and 60 matching organoid...

2026-02-08 | MTBLS7385 | MetaboLights
MetabolomicsUntargeted Serum Metabolomics Reveals Differential Signatures in Gallstone-Associated and Gallstone-Free Gallbladder Cancer

Gallbladder cancer (GBC) is an aggressive malignancy often associated with gallstones (GBCGS), a condition distinct from gallstone disease (GSD). Both GBC and GBCGS are rare, with unclear pathogenesis and no established biomarker-based solutions. This pilot study aimed to identify distinct metabo...

2025-12-22 | MTBLS12514 | MetaboLights
MetabolomicsUrine metabolomic profiling in two siblings with biallelic pathogenic ATG7 variants with healthy control
Ultra-rare biallelic ATG7 variants were recently reported in five families presenting with neurodevelopmental disorders. Two adult female siblings (P1 and P2) from one family carried compound heterozygous loss-of-function variants (c.1975C>T [p.Arg659]; c.2080-2A>G, 39,40NM_006395.2), resulting in u...
2026-09-30 | MTBLS15856 | MetaboLights
OtherProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts.
Data from ProteomeXchange, PXD ID: PXD001324. Experiment: P1, file: P1_Cyt_Near_4.mzml. Published as part of J Proteome Res. 2014 Sep 19. . From the Abstract: {{i}} Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-a...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM11210030024 | GPMDB
Resource Reanalysis 
OtherProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts.
Data from ProteomeXchange, PXD ID: PXD001323. Experiment: hmf_cyt_TGFb_1, file: hmf_cyt_TGFb_1_2.mzml. Published as part of J Proteome Res. 2014 Sep 19. . From the Abstract: {{i}} Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attribu...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32320003614 | GPMDB
Resource Reanalysis 
ProteomicsTargeted approach to determine the impact of cancer-associated protease variants
Several mechanisms of cancer progression, from tumour onset to metastasis, critically involve proteolytic activity. Studying the role of proteases in cancer, it is important to consider single nucleotide variants (SNVs) affecting the active site of proteases, that might impact cleavage specificity, ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD048501 | Pride
Snvs Meprin β Proteases Cancer Migration Spheroids Cancer-associated variants Cleavage specificity N-terminomics Organotypic brain slices 
GenomicsFunctionally Active Copy Number Variants Associated with Prostate Cancer Risk
Functionally Active Copy Number Variants Associated with Prostate Cancer Risk
PRJNA157931 | ENA
TranscriptomicsIdentification of circulating lncRNAs associated with gallbladder cancer risk by tissue-based preselection, cis-eQTL validation, and analysis of association with genotype-based expression
Long non-coding RNAs (lncRNAs) play key roles in cell processes and are good candidates for cancer risk prediction. Few studies have investigated the association between individual genotypes and lncRNA expression. Here we integrate three separate datasets with information on lncRNA expression only, ...
ORGANISM(S): Homo sapiens 
2022-01-17 | E-MTAB-11367 | biostudies-arrayexpress
GenomicsOvarian cancer associated variants
Targeted resequencing of the microRNAome and 3’UTRome reveals functional germline DNA variants with altered prevalence in epithelial ovarian cancer
PRJEB4945 | ENA
GenomicsSystematic Identification of Regulatory Variants Associated with Cancer Risk
Systematic Identification of Regulatory Variants Associated with Cancer Risk
PRJNA369067 | ENA
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