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UnknownAKT inhibitor Hu7691 induces differentiation of neuroblastoma cells.
Not available
S-EPMC10150122 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation of wild type, SET2 deletion, Rco1 PHD domain deletion and Eaf3 chromodomain deletion yeast using anti-acetyl-histone H4
Nucleosomes must be deacetylated behind elongating RNA polymerase II to prevent cryptic initiation of transcription within the coding region. RNA polymerase II signals for deacetylation through methylation of histone H3 lysine 36 (H3K36) which provides the recruitment signal for the Rpd3S deacetylas...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-16 | E-TABM-260 | biostudies-arrayexpress
UnknownBlockade of deubiquitinase YOD1 degrades oncogenic PML/RARα and eradicates acute promyelocytic leukemia cells
Not available
S-EPMC9279643 | biostudies-literature
GenomicsGenome-wide maps of Tbx3 binding sites in mouse ESCs
Induced pluripotent stem (iPS) cells can be obtained through the introduction of defined factors into somatic cells. The combination of Oct4, Sox2 and Klf4 (OSK) constitutes the minimal requirement for generating iPS cells from mouse embryonic fibroblasts (MEFs). Through the genomic analyses of ESC ...
ORGANISM(S): Mus musculus 
2009-12-04 | E-GEOD-19219 | biostudies-arrayexpress
UnknownRelationship between IDH1/2 and TERT promoter mutation and the prognosis of human glioma patients.
Not available
S-EPMC10214788 | biostudies-literature
UnknownBiology and genetic diversity of <i>Candida krusei</i> isolates from fermented vegetables and clinical samples in China.
Not available
S-EPMC11487970 | biostudies-literature
ProteomicsSDH deficiency-driven succinate accumulation dictates the drug resistance of AML through regulating p-UBC12/cullin activity
Drug resistance is vital for the poor prognosis of acute myeloid leukemia (AML) patients, but the underlying mechanism remains poorly understood. Given the unique microenvironment of bone marrow, we reasoned that drug resistance of AML might rely on distinct microenvironment-associated metabolic pro...
ORGANISM(S): Homo sapiens (Human) 
2024-08-28 | PXD047175 | Pride
Sdh deficiency  succinate  drug resistance  ubc12 phosphorylation  acute myeloid leukemia. 
GenomicsFYRN and FYRC domains of the histone demethylase, JMJ14, mediated chromatin binding and transgene silencing through a pair of NAC transcription factors
JmjC domain containing protein 14 (JMJ14) is an H3K4-specific histone demethylase that plays important roles in RNA-mediated gene silencing and flowering time regulation in Arabidopsis. However, how JMJ14 is recruited to their target genes remains unclear. Here, we show that the C-terminal FYRN and ...
ORGANISM(S): Arabidopsis thaliana 
2015-08-28 | E-GEOD-60084 | biostudies-arrayexpress
ProteomicsMouse skin pericytes LC-MSMS data
Proteomic analysis was conducted to investigate the potential downstream targets of MAT2A.
ORGANISM(S): Mus musculus (Mouse) 
2025-08-28 | PXD067803 | Pride
Lc-msms Mouse Pericytes 
ProteomicsMouse sertoli cells Palmitoylated protein MS
Elevated palmitic acid, a most abundant saturated fatty acid, is a risk factor for obesity complications. Here, we report that palmitic acid impairs spermatogenesis by inducing abnormal palmitoylation in Sertoli cells. Firstly, we proposed a correlation between palmitic acid and spermatogenesis by r...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD028778 | Pride
Mouse Ms Sertoli cells Palmitoylated protein 
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