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We used mass spectrometry-based proteomic identification to screen poly(ADP-ribosyl)ation (PARylation) targets. Af1521 is a PAR/MAR (mono(ADP-ribose))-binding module with strong affinity towards ADP-ribose. We used Af1521 to perform proteome-wide screening to identify protein that has been modified ...
ORGANISM(S): Homo sapiens (Human) 
2026-10-17 | PXD064443 | Pride
To unravel the molecular mechanism involved in PARP1-mediated MLKL PARylation, the potential PARylation sites were identified in MLKL amino acid sequence by LC-MSMS.
ORGANISM(S): Homo sapiens (Human) 
2026-10-17 | PXD064394 | Pride
Hypertensive disorder in pregnancy (HDP) refers to a series of diseases that cause the hypertension during pregnancy, including HDP, preeclampsia (PE) and eclampsia. This study screens differentially expressed proteins of placenta tissues in PE cases using 2D LC-MS/MS quantitative proteomics strateg...
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD006755 | Pride
Solexa sequencing technology was used to perform high throughput sequencing of the small RNA library from the cold treatment of tea leaves. Subsequently, aligning these sequencing date with plant known miRNAs, we characterized 112 C. sinensis conserved miRNAs. In addition, 215 potential candidate mi...
ORGANISM(S): Camellia sinensis 
H441 cell proteome was sequenced via SILAC and LC-MS/MS method to identify hypoxia-responsive proteins
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-05-15 | MSV000081087 | MassIVE
To connect aberrant phospho-signaling events to therapeutic vulnerabilities in hepatocellular carcinoma (HCC), we performed a mass-spectrometry-based phosphoproteomic quantification of human HCC tumors, adjacent tissues and cell lines. We developed an integrated pipeline as the inference of druggabl...
ORGANISM(S): Homo Sapiens 
2023-01-02 | PXD023840 |
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