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ProteomicsNFU3 is an Fe-S cluster carrier protein that is implicated in photosystem I maturation (PsaA, PsaB, PsaC). Label free proteomic approach on nfu3-2 mutant allow the discovery of new potential client proteins
NFU3 is a Fe-S cluster carrier protein of Arabidopsis that allow the maturation of Fe-S cluster proteins in chloroplast. proteomic Label free experiment was carried out to monitored wich Fe-S cluster proteins are affected in nfu3-2 mutant background
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-09-09 | PXD020228 | Pride
Fe-s cluster photosynthesis 
TranscriptomicsThe SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in the mouse genome
Pseudoautosomal regions (PAR1 and PAR2) in eutherians retain homologous regions between the X and Y chromosomes that play a critical role in the obligatory X-Y crossover during male meiosis. Genes that reside in the PAR1 are exceptional in that they are rich in repetitive sequences and undergo a ve...
ORGANISM(S): Mus musculus 
2009-08-01 | E-GEOD-12454 | biostudies-arrayexpress
TranscriptomicsUnraveling the KNOTTED1 regulatory network in maize meristems
KNOTTED1(KN1)-like homeobox (KNOX) transcription factors function in plant meristems, self-renewing structures consisting of stem cells and their immediate daughters. Despite their importance for plant development, the genomic network targeted by KNOX proteins is poorly understood. Using ChIP-seq, w...
ORGANISM(S): Zea mays 
2012-09-04 | E-GEOD-38487 | biostudies-arrayexpress
TranscriptomicsMechanical loading and gene expression - Microarray study
Skeletal integrity in humans and animals is maintained by daily mechanical loading. It has been widely accepted that osteocytes function as mechanosensors. Many biochemical signaling molecules are involved in the response of osteocytes to mechanical stimulation. The aim of this study was to identify...
ORGANISM(S): Rattus norvegicus 
2013-11-21 | E-GEOD-50707 | biostudies-arrayexpress
TranscriptomicsA natural expression variant reveals a novel mechanism of insect resistance in boreal forest trees.
We report the discovery of a beta-glucosidase gene (PgM-NM-2glu-1) whose expression underpins natural resistance to a major forest pest, the spruce budworm (SBW) in white spruce (Picea glauca (Voss.) Moench). We performed a microarray experiment to compare resistant (R) and non-resistant (N-R) trees...
ORGANISM(S): Picea glauca 
2014-05-06 | E-GEOD-57301 | biostudies-arrayexpress
GenomicsTCC in pluripotent and differentiated cells
Regulation of gene expression underlies the establishment and maintenance of cell identity. Chromatin structure and gene activity are linked. Recently CTCF anchored loops have been described as major features of chromatin organisation. However, the dynamics and role for these structures in differ...
ORGANISM(S): Mus musculus 
2018-11-08 | E-MTAB-4870 | biostudies-arrayexpress
GenomicsProfiling Genome-wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells
We have engineered the chromatin-modifying apparatus and formulated a novel technology, termed Clickable Chromatin Enrichment with parallel DNA sequencing (CliEn-seq), to probe genome-wide chromatin modification within living cells. Examine (E)-hex-2-en-5-ynylation mediated by engineered G9a Y1154A ...
ORGANISM(S): Homo sapiens 
2013-03-04 | E-GEOD-42792 | biostudies-arrayexpress
TranscriptomicsThe ERRalpha metabolic nuclear receptor controls growth of colon cancer cells
Estrogen-Related Receptor alpha (ERRα) is a nuclear receptor that acts principally as a regulator of metabolism processes particularly in tissues subjected to high-energy demand. Besides its implication in energy metabolism and mitochondrial biogenesis, ERRα was recently associated with tumorigene...
ORGANISM(S): Homo sapiens 
2013-06-06 | E-GEOD-38690 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Picea glauca xylem and phloem
In this experiment we compared the transcriptomes of xylem and phloem.
ORGANISM(S): Picea glauca 
2009-03-04 | E-MEXP-1489 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Clear cell renal carcinoma
Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment with targeted tyrosine kinase inhibitors (TKIs) is a challenge. Our aim was to identify molecular markers associated with outcome in m-ccRCC patients treated with sunitinib. A Cartes d’Ident...
ORGANISM(S): Homo sapiens 
2015-01-27 | E-MTAB-3267 | biostudies-arrayexpress
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