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ProteomicsMapping the spatial proteome of metastatic cells in colorectal cancer
Here, we aimed to study metastasis mechanisms using spatial proteomics applied to the KM12 cell model of metastasis. KM12 cells were metabolically labelled using SILAC. SILAC has been successfully used for the analysis of proteome turnover and for the identification of changes in proteome localizati...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-23 | MSV000088431 | MassIVE
ProteomicsMapping the spatial proteome of metastatic cells in colorectal cancer
Here, we aimed to study metastasis mechanisms using spatial proteomics applied to the KM12 cell model of metastasis. KM12 cells were metabolically labelled using SILAC. SILAC has been successfully used for the analysis of proteome turnover and for the identification of changes in proteome localizati...
ORGANISM(S): Homo sapiens (Human) 
2017-09-11 | PXD006656 | Pride
Subcellular fraction Colorectal cancer Silac Lc-ms/ms 
ProteomicsProteomic characterization of the role of Snail1 in the differentiation of 3T3-L1 fibroblasts
Snail1 is a transcriptional repressor required for a correct embryonic development. In cancer, Snail1 promotes the epithelial to mesenchymal transition in tumorigenic epithelial cells. In this work, we have analyzed the control of Snail1 in the differentiation of the 3T3-L1 cell line derived from mu...
ORGANISM(S): Mus musculus (Mouse) 
2015-01-06 | PXD001529 | Pride
Adipogenesis Il-17 Obesity Nr2f6 Snail Silac Ltq orbitrap velos 
UnknownNovel snail1 target proteins in human colon cancer identified by proteomic analysis.
Not available
S-EPMC2857666 | biostudies-literature
UnknownCystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression.
Not available
S-EPMC4646312 | biostudies-literature
ProteomicsChr16-HPP.Pilot experiment.JPR HPP Special issue
"The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To characterize t...
ORGANISM(S): Homo sapiens (Human) 
2013-01-11 | PXD000039 | Pride
Human "hpp Miape" 
TranscriptomicsHuman cystatin D (CST5) locates in the nucleus at sites of active transcription and regulates gene expression
Cystatin D (CST5) is an inhibitor of several proteases of the cathepsin family that inhibits cell proliferation, migration and invasion of colon carcinoma cells. Some of these effects are unrelated to its antiprotease activity. Here, we use genome-wide expression microarrays to show that cystatin D ...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-45904 | biostudies-arrayexpress
ProteomicsChr16-HPP. Shotgun Analysis improvement. JPR HPP Special issue 2013. Jurkat Cell line.
The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To do this study f...
ORGANISM(S): Homo sapiens (Human) 
2013-09-05 | PXD000443 | Pride
Chromosome centric Networking Miape Hpp 
ProteomicsChr16-HPP. Shotgun Analysis improvement. JPR HPP Special issue 2013. MCF7 Cell line.
The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To do this study f...
ORGANISM(S): Homo sapiens (Human) 
2013-09-04 | PXD000442 | Pride
Chromosome centric Networking Miape Hpp 
ProteomicsChr16-HPP. Shotgun Analysis improvement. JPR HPP Special issue 2013. CCD18 Cell line.
The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To do this study f...
ORGANISM(S): Homo sapiens (Human) 
2013-09-05 | PXD000449 | Pride
Chromosome centric Networking Miape Hpp 
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