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ProteomicsThe E3 ligase TRIM25 impairs apoptotic cell death in colon carcinoma cells through hnRNPH1-triggered destabilization of caspase-7 mRNA
Therapy resistance is still a major reason for treatment failure in colorectal cancer (CRC). Previously, we identified the E3 ubiquitin ligase TRIM25 as a novel suppressor of caspase-2 translation, thereby contributing to apoptosis resistance of CRC cells towards chemotherapeutic drugs. We herein re...
ORGANISM(S): Homo sapiens (Human) 
2023-01-05 | PXD037182 | Pride
Trim25 Colon carcinoma cells Caspase-7 Hnrnph1 Rna binding proteins Apoptosis 
OtherExecutioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart.
Data from PeptideAtlas, [[http://www.peptideatlas.org/PASS/PASS00689 PASS00689]]. File: JAL_DanSanc_Hrt_iTRAQ_Fr6.mzml. Published as part of PLoS One. 2015 Jun 29;10(6):e0131411 . From the Abstract: {{i}} Executioner caspase-3 and -7 are proteases promoting cell death but non-apoptotic roles are be...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32320017677 | GPMDB
ProteomicsMass Spectra of a caspase 7 cleavage fragment of SATB2
This data identifies the cleavage fragment of an in vitro reaction between recombinant, active caspase 7 and recombinant SATB2. The data confirms that this fragment is indeed a part of SATB2 and this information was used to further our investigation into the role SATB2 in mammalian skeletal muscle s...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-08 | MSV000085254 | MassIVE
GenomicsEffect of caspase-3 and -7 knockout on doxorubicin treated B16 melanoma cells
Effect of caspase-3 and -7 knockout on doxorubicin treated B16 melanoma cells
PRJNA865449 | ENA
ProteomicsLegionella pneumophila effector LegK3 directly phosphorylates multiple caspases involved in apoptosis signaling, including Caspase-3, Caspase-7, and Caspase-9
Legionella pneumophila effector Legk3 phosphorylates caspase3/7/9 under infection, transfection, or in vitro purification condition
ORGANISM(S): Homo Sapiens 
PXD054358 |
ProteomicsHuman recombinant caspase 2-3-7
COFRADIC identification of human recombinant caspase-2, -3, -7 cleavage sites
ORGANISM(S): Homo sapiens (Human) 
2012-08-15 | PRD000557 | Pride
TranscriptomicsEffect of caspase-3 and -7 knockout on doxorubicin treated B16 melanoma cells
To measure the immunosuppressive effect of caspase-3 and -7 in apoptosis, we generated B16 sgCTRL and sgCasp3/7 cells and treated them with doxorubicin
ORGANISM(S): Mus musculus 
2022-08-05 | GSE210377 | GEO
UnknownExecutioner caspase-3 and caspase-7 are functionally distinct proteases.
Not available
S-EPMC2529079 | biostudies-literature
UnknownCalpain-1 cleaves and activates caspase-7.
Not available
S-EPMC2757245 | biostudies-literature
TranscriptomicsMiR-106b-25 cluster targets caspase 7 and focal adhesion in human prostate cancer
We and others previously reported that the miR-106b-25 microRNA cluster is a candidate oncogene in human prostate cancer. Here, we made the novel observation that miR-106b-25 expression is further up-regulated in distant metastasis. Moreover, increased tumor miR-106b expression was associated with e...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-34893 | biostudies-arrayexpress
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