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no omics definedTranscription profiling of Candida albicans biofilm exposed to amphotericin B, fluconazole or two concentrations of caspofungin
30h of growth biofilms in microfermentors were exposed to caspofungin 0.5 µg/ml, caspofungin 5 µg/ml, fluconazole 80 µg/ml or amphotericin B 8 µg/ml. Control and antifungal-exposed biofilms were recovered at t= 0, 30, 60 and 120 min post exposure to antifungal.
ORGANISM(S): Candida albicans 
2010-03-02 | E-MEXP-2436 | biostudies-arrayexpress
ProteomicsProteome of candida glabrata after Caspofungin exposure
Caspofungin resistance is a great concern, as the echinocandin drugs are recommended as first-line therapy for invasive candidiasis. Echinocandin resistance is conferred by mutations in FKS genes. Nevertheless, some pathways which regulate cellular stress responses could be crucial for enabling the ...
ORGANISM(S): Candida glabrata (Yeast) (Torulopsis glabrata) 
2022-04-04 | PXD021578 | Pride
Lc ms/ms Candida glabrata Caspofungin Preteome 
TranscriptomicsCaspofungin enhances antifungal immunity in human blood through transcriptional reprogramming
This study investigates how the echinocandin antifungal drug caspofungin (CAS) modulates early immune responses during Candida albicans bloodstream infection. Echinocandin-susceptible (ECHS/FKSwt) and echinocandin-resistant (ECHR/FKSmut) C. albicans candidemia strains were used to determine whether ...
ORGANISM(S): Homo sapiens 
2026-01-31 | E-MTAB-16334 | biostudies-arrayexpress
ProteomicsCaspofungin induced cell wall changes of Candida species influences macrophage interactions
The structure and composition of the cell walls of different Candida species alone and in response to the antifungal drug, caspofungin, were investigated. The observed differences were used to evaluate how changes at the fungal cell surface affect interactions with macrophages.
ORGANISM(S): Candida glabrata (Yeast) (Torulopsis glabrata) Candida tropicalis MYA-3404 Candida dubliniensis Candida parapsilosis Clavispora lusitaniae ATCC 42720 Meyerozyma guilliermondii ATCC 6260 
2020-05-20 | PXD019293 | Pride
Lc-msms Candida Cell wall 
GenomicsCaspofungin interferes with Candida albicans iron homeostasis
Caspofungin interferes with Candida albicans iron homeostasis
PRJNA1178708 | ENA
GenomicsWhole genome sequencing of caspofungin adaptors in Candida parapsilosis
Candida parapsilosis wild type strain #12108 was exposed to 400ng/ml caspofungin. Randomly 30 adaptors were chosen. These adaptors as well as the parent were sequenced.
ORGANISM(S): Candida parapsilosis 
2022-11-05 | E-MTAB-12335 | biostudies-arrayexpress
ProteomicsIntegration of multilevel OMICs data based on the identification of regulatory modules from protein-protein interaction networks
Complex scientific experiments provide researchers with a wealth of data and knowledge from heterogeneous sources. Analyzed in its entirety, OMICs data provide a deep insight into the overall biological processes of organisms. However, the integration of data from different cellular levels (e.g., tr...
ORGANISM(S): Neosartorya fumigata (Aspergillus fumigatus) 
2018-10-25 | PXD008153 | Pride
Caspofungin Proteomics Lc-ms Aspergillus fumigatus Secretome 
TranscriptomicsWhole genome sequencing of caspofungin adaptors in Candida albicans
Approximately 200 cells of Candida albicans lab strain SC5314 were spread on YPD plates supplemented with 2 fold increase from 50 ng/ml to 12800ng/ml caspofungin. All adaptors appeared were collected. Randomly 36 tolerant adaptors were sequenced.
ORGANISM(S): Candida albicans 
2023-09-15 | E-MTAB-12336 | biostudies-arrayexpress
GenomicsWhole genome sequencing of caspofungin adaptors in Candida auris
Candida auris clade III isolate B12039 was spread on YPD plate supplemented with 250 ng/ml, 500 ng/ml, 1000 ng/ml, and 2000 ng/ml of caspofungin. In total, 33 adaptors were chosen for further analysis. We did sequencing of them as as well as the parent. 9 adaptors (250-1 - 250-9) were obtained from ...
ORGANISM(S): Candida auris 
2021-07-23 | E-MTAB-10627 | biostudies-arrayexpress
ProteomicsCaspofungin-induced Responses in the Planktonic Cells and Biofilms of Candida albicans
This project investigated the signature profiles of C. albicans planktonic cells and biofilms in response to caspofungin.
ORGANISM(S): Candida Albicans 
2021-01-08 | PXD023480 |
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