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TranscriptomicsTranscription profiling of mouse WT and Cav-3 knockouts on FVB/N genetic background mammary glands reveals loss of caveolin-3 induces the development of a lactogenic microenvironment
Here, we show that functional loss of a single gene is sufficient to confer constitutive milk protein production and protection against mammary tumor formation. Caveolin-3 (Cav-3), a muscle-specific caveolin-related gene, is highly expressed in striated and smooth muscle cells. We demonstrate that C...
ORGANISM(S): Mus musculus 
2009-01-31 | E-GEOD-12881 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse caveolin-3 knockout hearts
Energy Substrate Uptake and Metabolism are Preserved in Hypertrophic Caveolin-3 Knockout Hearts Experiment Overall Design: 3 wild types, 3 knockouts
ORGANISM(S): Mus musculus 
2009-03-15 | E-GEOD-10848 | biostudies-arrayexpress
ProteomicsThe ambiguous Caveolin-3 G55S sequence variant: Muscle biopsy findings and cell biological analysis
Caveolins are structural and functional proteins in plasma membrane invaginations called caveolae. Mutations in Caveolin-3 cause myopathies of variable severity. The pathogenicity of the Caveolin-3 variant G55S is still unclear. Here, we report on three patients suffering from mild to moderate myopa...
ORGANISM(S): Homo sapiens (Human) 
2018-07-05 | PXD003719 | Pride
Lgmd1d Rcmh Caveolin-3 Proteome profile of muscle cells 
TranscriptomicsCaveolin-3 Knockout Hearts
Energy Substrate Uptake and Metabolism are Preserved in Hypertrophic Caveolin-3 Knockout Hearts Keywords: gene knockout
ORGANISM(S): Mus musculus 
2009-03-04 | GSE10848 | GEO
GenomicsMus musculus
Caveolin-3 Knockout Hearts
PRJNA107339 | ENA
UnknownCaveolin-3 and Caveolin-1 Interaction Decreases Channel Dysfunction Due to Caveolin-3 Mutations.
Not available
S-EPMC10816214 | biostudies-literature
TranscriptomicsLoss of Caveolin-3 Induces the Development of a Lactogenic Microenvironment
Here, we show that functional loss of a single gene is sufficient to confer constitutive milk protein production and protection against mammary tumor formation. Caveolin-3 (Cav-3), a muscle-specific caveolin-related gene, is highly expressed in striated and smooth muscle cells. We demonstrate that C...
ORGANISM(S): Mus musculus 
2009-01-26 | GSE12881 | GEO
ProteomicsCardioprotection by selective SGLT2 inhibitors in a non-diabetic mouse model of myocardial ischemia/reperfusion injury: a class or a drug effect?
Major clinical trials with sodium glucose co-transporter-2 inhibitors (SGLT-2i) exhibit protective effects against heart failure events, whereas inconsistencies regarding the cardiovascular death outcomes are observed. Therefore, we aimed to compare the selective SGLT-2i empagliflozin (EMPA), dapagl...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-12-17 | MSV000088582 | MassIVE
UnknownMuscular atrophy of caveolin-3-deficient mice is rescued by myostatin inhibition.
Not available
S-EPMC1592547 | biostudies-literature
TranscriptomicsLS001A: Aging/Early Degeneration Of The Intervertebral Disc Involves Downregulation Of Canonical Wnt Signaling and Caveolin-1 expression
Objective: Aging and early degeneration of the intervertebral disc (IVD) involves the substition of notochordal cells (NCs) in the nucleus pulposus (NP) by chondrocyte-like cells (CLCs). This study investigated the gene expression profiles involved in this process using NP tissue from both non-chond...
ORGANISM(S): Canis lupus familiaris 
2013-01-31 | E-GEOD-35717 | biostudies-arrayexpress
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