Cb2 receptor - OmicsDI

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Unknown_m_8.335 (1)
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N-acetyl groups (glycoproteins) (1)
Unknown_s_1.35 (1)
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Modelling Approach

Ordinary differential equation model (2)

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Lab affiliation

Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK (2)
Cambridge Institute for Medical Research, Hills Road, Cambridge, CB2 0XY (1)
Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, CB2 0XY, UK (1)
Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK (1)
Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY (1)
Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK (1)
Cancer Research UK, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE (1)
Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand (1)
Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK. (1)
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK. (1)
Division of Cell Biology MRC Laboratory of Molecular Biology Francis Crick Avenue Cambridge CB2 0QH, UK (1)
Head of Proteomics CRUK Cambridge Institute Cambridge University Robinson Way Cambridge CB2 0RE UK Email: clive.d’santos@cruk.cam.ac.uk Phone: +44 1223 769677 (1)
Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil (1)
MRC Laboratory of Molecular Biology Francis Crick Avenue Cambridge Biomedical Campus CB2 0QH Cambridge (1)
MRC Laboratory of Molecular Biology Francis Crick Avenue Cambridge Biomedical Campus CB2 0QH Cambridge UK (1)
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK (1)
Molecular Physiology, Leiden Institute for Chemistry, Leiden University, The Netherlands (1)
Senior Lecturer in Transfusion Medicine / Consultant Haematologist, University of Cambridge / NHS Blood and Transplant, Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Puddicombe Way, Cambridge, CB2 0AW, United Kingdom (1)
University of Cambridge, Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, CB2 0RE, UK (1)

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Cannabinoids modulate proliferation, differentiation, and migration signaling pathways in oligodendrocytes

To elucidate the specific molecular signals associated with the activation or blockade of CB1 and CB2 receptors in this glial cell, mass spectrometry-based proteomics and in silico biology tools were used to determine which signaling pathways and molecular mechanisms are triggered in a human oligode...

ORGANISM(S): Homo sapiens (Human)

2022-06-09 | PXD031923 | Pride

Role of CB2 in adipose tissue ILC2s

PRJNA1114121 | ENA

Cannabinoid CB2 receptor drives trastuzumab resistance and predicts durable anti-HER2 response

PRJNA1282023 | ENA

Role of CB2 in adipose tissue ILC2s

Development of type 2 diabetes mellitus (T2DM) is associated low-grade chronic type 2 inflammation and disturbance of glucose homeostasis. Group 2 innate lymphoid cells (ILC2s) play a critical role in maintaining adipose homeostasis via production of type 2 cytokines. Here, we demonstrate that CB2, ...

ORGANISM(S): Mus musculus

2024-08-16 | GSE268067 | GEO

A selective photoaffinity probe enables assessment of cannabinoid CB2 receptor expression and ligand engagement in human cells

Chemical tools and methods that report on G protein-coupled receptor (GPCR) expression levels and receptor occupancy by small molecules are highly desirable. We report the development of LEI121 as a photoreactive probe to study the type 2 cannabinoid receptor (CB2R), a promising GPCR to treat tissue...

ORGANISM(S): Homo sapiens (Human) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

2018-06-15 | PXD008460 | Pride

Target engagement Cb2 receptor Gpcrs Photo-affinity labeling Bio-orthogonal chemistry

Peripheral cannabinoid receptor, CB2, regulates bone mass.

Not available

S-EPMC1334629 | biostudies-literature

Crystal Structure of the Human Cannabinoid Receptor CB2.

Not available

S-EPMC6713262 | biostudies-literature

Cryo-EM Structure of the Human Cannabinoid Receptor CB2-G_i Signaling Complex.

Not available

S-EPMC8247115 | biostudies-literature