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The CCA-adding enzyme adds CCA to the 3' ends of transfer RNAs (tRNAs), a critical step in tRNA biogenesis that generates the amino acid attachment site. We found that the CCA-adding enzyme plays a key role in tRNA quality control by selectively marking unstable tRNAs and tRNA-like small RNAs for de...
ORGANISM(S): Saccharomyces cerevisiae 
Cholangiocarcinomas (CCAs) are heterogeneous biliary cancers with dismal prognosis. Their etiologies remain mostly unclear, although primary sclerosing cholangitis (PSC) is a well-known risk factor. There is an urgent need of accurate non-invasive biomarkers for early CCA diagnosis and to predict pa...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD026197 | Pride
FOSL1 target genes in cholangiocarcinoma (CCA) cells
beta catenin in CCA cell lines and patient samples
16S V4V5 sequencing of Tara Pacific crustose coralline algae (CCA) samples
MiRNA expression profiling in cholangiocarcinoma (CCA) cells treated with TGF-b
Treatment of cholangiocarcinoma using humanized monoclonal antibodies targeting Claudin-1(CCA organoids)
Treatment of cholangiocarcinoma using humanized monoclonal antibodies targeting Claudin-1 (CCA patient tissues)
Differential plasma proteomes of the patients with Opisthorchiasis viverrini and cholangiocarcinoma identifies polymeric immunoglobulin receptor as potential biomarker
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD028152 | Pride
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