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ProteomicsProteomic Profiling of Uveal Melanoma Cells Treated with DHA and CCCP
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, with limited treatment options and poor clinical outcomes. Dihydroartemisinin (DHA), have shown anti-tumor activity in UM, though typically at high concentrations. This study investigates the synergistic anti-tumor effe...
ORGANISM(S): Homo sapiens (Human) 
2025-06-10 | PXD064150 | Pride
Human Uveal melanoma Dha Cccp 
TranscriptomicsTime-series of transcriptome analysis of Bacillus subtilis response to 25 mM potassium acetate and 0.85 M-BM-5M CCCP
The advent of M-bM-^@M-^XomicsM-bM-^@M-^Y techniques bear significant potential for the assessment of the microbiological stability of foods. This requires the integration of molecular data with their implication for cellular physiology. Here we performed a comparative physiological and transcriptio...
ORGANISM(S): Bacillus subtilis 
2014-04-11 | E-GEOD-55051 | biostudies-arrayexpress
GenomicsTranscriptome analysis after CCCP and/or DHA treatment in uveal melanoma cells
Transcriptome analysis after CCCP and/or DHA treatment in uveal melanoma cells
PRJNA736402 | ENA
TranscriptomicsGene expression in Escherichia coli treated with human PGRP, gentamicin, and CCCP
Human Peptidoglycan Recognition Proteins (PGRPs) kill bacteria, likely by over-activating stress responses in bacteria. To gain insight into the mechanism of PGRP killing of Escherichia coli and bacterial defense against PGRP killing, gene expression in E. coli treated with a control protein (bovine...
ORGANISM(S): Escherichia coli 
2014-07-25 | E-GEOD-44211 | biostudies-arrayexpress
TranscriptomicsGene expression in Bacillus subtilis treated with human PGRP, gentamicin, and CCCP
Human Peptidoglycan Recognition Proteins (PGRPs) kill bacteria, likely by over-activating stress responses in bacteria. To gain insight into the mechanism of PGRP killing of Bacillus subtilis and bacterial defense against PGRP killing, gene expression in B. subtilis treated with a control protein (b...
ORGANISM(S): Bacillus subtilis 
2014-07-25 | E-GEOD-44212 | biostudies-arrayexpress
GenomicsTime-series RNA-seq of U2OS cells following CCCP-induced mitochondrial damage and recovery upon drug washout
Time-series RNA-seq of U2OS cells following CCCP-induced mitochondrial damage and recovery upon drug washout
PRJNA1507420 | ENA
TranscriptomicsTime-series RNA-seq of U2OS cells following CCCP-induced mitochondrial damage and recovery upon drug washout
Mitochondria are continuously exposed to damage that contributes to aging and disease. While prolonged mitochondrial damage triggers mitophagy, how cells respond to transient damage remains unclear. To investigate the transcriptional programs underlying transient mitochondrial damage and subsequent ...
ORGANISM(S): Homo sapiens 
2026-08-05 | GSE342354 | GEO
GenomicsGenome-wide Transcriptional Profiling of Bacillus subtilis in response to valinomycin and CCCP
Genome-wide Transcriptional Profiling of Bacillus subtilis in response to valinomycin and CCCP
PRJNA672980 | ENA
TranscriptomicsTranscriptome analysis after CCCP and/or DHA treatment in uveal melanoma cells
In order to study the mechanism of CCCP combined with DHA treatment in uveal melanoma, we applied RNA-seq to identify its target genes in ocular melanoma.
ORGANISM(S): Homo sapiens 
2024-06-01 | GSE176474 | GEO
UnknownCCCP inhibits DPV infection in DEF cells by attenuating DPV manipulated ROS, apoptosis, and mitochondrial stability.
Not available
S-EPMC10891340 | biostudies-literature
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