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ProteomicsCharacterization of MACS isolated microglia cells (CD11b positive cells) in comparison to all non-CD11b positive cells (termed non-target cell fraction (NTCF)) with proteomics
Microglia isolation from adult mouse brains remains difficult in comparison to microglia isolation from brains from newborn mouse brains as connective tissue, extracellular matrix materials and thicker myelin sheaths substantially influence traditional isolation protocols used with newborn mouse bra...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-22 | PXD031973 | Pride
Cd11b positive cells Proteomics Microglia Ntcf 
TranscriptomicsTranscription profiling of mouse FLT3+/CD11b+ Dendritic cell (DC) progenitor
FLT3+/CD11b+ Dendritic cell (DC) progenitor was amplified in vitro from mouse bone marrow.
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-692 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine E10.5 TLR2+ CD11b+ embryonic phagocytes by comparative microarray analyses
The detection of Toll-like receptor 2 (TLR2) expression on E10.5 early embryonic phagocytes prompted us to determine the list of markers co-expressed with TLR2 in a cell-type specific manner. Thus, a comparative expression profiling of cDNAs between murine E10.5 TLR2+ CD11b+ embryonic cells and TLR2...
ORGANISM(S): Mus musculus 
2014-12-01 | E-MTAB-1537 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of CX3CR1high CD11b+ CD11c+ cells in murine intestinal lamina propria
Several innate immune cell subsets have recently been identified to maintain gut homeostasis in both human and mice. Among these subsets, CX3CR1high CD11b+ CD11c+ cells contribute to intestinal tolerance through various mechanisms in mice. However, whether tolerogenic innate myeloid cells are presen...
ORGANISM(S): Mus musculus 
2016-07-17 | E-GEOD-79628 | biostudies-arrayexpress
TranscriptomicsGene Expression Analysis of Host Immune Responses in CD11b positive cells isolated from lungs of the UV inactivated SARS-CoV-immunized mice following Lethal SARS-CoV Infection
To better understand the biological pathways by which UV inactivated SARS-CoV-induced pulmonary eosinophilia occurs, we examined global transcriptional changes in macrophages from the lungs of mouse. Female BALB/c mice were used at 21 weeks of age. Mice were subcutaneously immunized with UV inactiv...
ORGANISM(S): Mus musculus 
2014-05-22 | E-GEOD-50855 | biostudies-arrayexpress
TranscriptomicsDifferentially expressed genes of CD11b+Gr-1+ myeloid cells
Differentially expressed genes of CD11b+Gr-1+ immature myeloid cells (IMCs) in the bone marrow and colonic tumor setting of histidine decarboxylase (HDC)-KO mice were examined by microarray (Affymetrix Mouse 430.2 array). Myeloid differentiation-related candidate genes were sought to be isolated and...
ORGANISM(S): Mus musculus 
2010-12-15 | E-GEOD-23502 | biostudies-arrayexpress
TranscriptomicsRNA-Seq global gene expression of four Dendritic cells subpopulations from lung (CD8+ and CD8- pDCs, CD103-CD11b+ and CD103+CD11b- cDCs) of influenza infected mice at four time points following infection
Hundreds of immune cell types work in coordination to maintain tissue homeostasis. Upon infection, dramatic changes occur with the localization, migration and proliferation of the immune cells to first alert the body of the danger, confine it to limit spreading, and finally extinguish the threat and...
ORGANISM(S): Mus musculus 
2014-03-03 | E-GEOD-49932 | biostudies-arrayexpress
MetabolomicsBranched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming

Macrophages are prominent immune cells in the tumor microenvironment that can be educated into pro-tumoral phenotype by tumor cells to favor tumor growth and metastasis. The mechanisms that mediate a mutualistic relationship between tumor cells and macrophages remain poorly characterized. Here, w...

2022-10-03 | MTBLS4497 | MetaboLights
TranscriptomicsTranscription profiling of mouse dendritic cell differentiation from dendritic cell progenitor in vitro
FLT3+CD11b+ DC progenitor was amplified in vitro from mouse bone marrow. DC were differentiated using GM-CSF and analyzed at day 7 and day 10 of differentiation and after 16h TNFalpha stimulation at day 10
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-575 | biostudies-arrayexpress
TranscriptomicsGene expression data from CD11b-positive myeloid cells infiltrating tumors after local irradiation
Analysis of global gene expression in myeloid cells infiltrating tumors after irradiation. Cell death induces recruitment of myeloid cells into irradiated tumors thereby stimulating tumor recurrence. Results provide insights into molecular mechanisms regulating tumorigenic functions of myeloid cells...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-45180 | biostudies-arrayexpress
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