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ProteomicsCharacterization of MACS isolated microglia cells (CD11b positive cells) in comparison to all non-CD11b positive cells (termed non-target cell fraction (NTCF)) with proteomics
Microglia isolation from adult mouse brains remains difficult in comparison to microglia isolation from brains from newborn mouse brains as connective tissue, extracellular matrix materials and thicker myelin sheaths substantially influence traditional isolation protocols used with newborn mouse bra...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-22 | PXD031973 | Pride
Cd11b positive cells Proteomics Microglia Ntcf 
TranscriptomicsGene Expression Analysis of Host Immune Responses in CD11b positive cells isolated from lungs of the UV inactivated SARS-CoV-immunized mice following Lethal SARS-CoV Infection
To better understand the biological pathways by which UV inactivated SARS-CoV-induced pulmonary eosinophilia occurs, we examined global transcriptional changes in macrophages from the lungs of mouse. Female BALB/c mice were used at 21 weeks of age. Mice were subcutaneously immunized with UV inactiv...
ORGANISM(S): Mus musculus 
2014-05-22 | E-GEOD-50855 | biostudies-arrayexpress
UnknownPositive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer.
Not available
S-EPMC7253726 | biostudies-literature
UnknownIL27 controls skin tumorigenesis via accumulation of ETAR-positive CD11b cells in the pre-malignant skin.
Not available
S-EPMC5363575 | biostudies-literature
TranscriptomicsGene expression data from CD11b-positive myeloid cells infiltrating tumors after local irradiation
Analysis of global gene expression in myeloid cells infiltrating tumors after irradiation. Cell death induces recruitment of myeloid cells into irradiated tumors thereby stimulating tumor recurrence. Results provide insights into molecular mechanisms regulating tumorigenic functions of myeloid cells...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-45180 | biostudies-arrayexpress
UnknownCD45/CD11b positive subsets of adult lung anchorage-independent cells harness epithelial stem cells in culture.
Not available
S-EPMC4434406 | biostudies-literature
ProteomicsQuantitative Proteomics of Acutely Isolated Mouse Microglia Identifies Novel Immune Alzheimer's Disease-related Proteins
Microglia are innate immune cells of the brain that perform phagocytic and inflammatory functions in disease conditions. Transcriptomic studies of acutely-isolated microglia have provided novel insights into their molecular and functional diversity in homeostatic and neurodegenerative disease states...
ORGANISM(S): Mus musculus (Mouse) 
2018-09-18 | PXD009137 | Pride
Cd11b-positive Brain resident microglia 
GenomicsscRNAseq of hepatic CD11b positive immune cells from uninjured control (Ctrl) and liver fibrosis resolved (RES) mice
scRNAseq of hepatic CD11b positive immune cells from uninjured control (Ctrl) and liver fibrosis resolved (RES) mice
PRJNA783872 | ENA
TranscriptomicsIRF8-regulated genes in primary CD11 b cells
Transcriptional profiling of IRF8-regulated genes in mouse CD11b-positive primary cells. CD11b-positive cells were isolated from spleens of age-matched wt and IRF8 KO mice, the compared for their gene expression profiles. The objective is to identify genes that are regulated by IRF8 in CD11b-positiv...
ORGANISM(S): Mus musculus 
2011-10-19 | E-GEOD-31464 | biostudies-arrayexpress
TranscriptomicsPeri-alloHCT IL-33 administration expands recipient T regulatory cells that protect mice against acute GvHD
Graft-versus-Host Disease (GvH) is the excessive inflammatory response by mature T cells contained in the graft during bone marrow transplantation. The allogeneic T cells recognize self-antigens as foreign and systemically attack multiple organs mostly with epithelial structures such as the skin, li...
ORGANISM(S): Mus musculus 
2016-06-27 | E-MTAB-4677 | biostudies-arrayexpress
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