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ProteomicsCD147 mutants affinity purification mass spectrometry from human T cells
CD147 is known as tumor and regulatory T cell marker and as regulator of chemotaxis, stress response or immune cell function; however, the mode of action of CD147 remains incompletely understood. Using affinity purification mass spectrometry (AP-MS) of HA-tagged CD147 swap and deletion mutants, we e...
ORGANISM(S): Homo sapiens (Human) 
2016-01-28 | PXD003029 | Pride
Human Jurkat Affinity purification Primary t cells Cd147 Lc-ms/ms 
ProteomicsLateral interactions between B7-H3 and CD147 are essential for stemness in breast cancer: a novel insight from proximal proteome analysis
Oncogenic cell-surface membrane proteins contribute to the phenotypic and functional characteristics of cancer stem cells (CSCs). We quantitatively analyzed cell-surface membrane proteins that are in close proximity to CD147 in CSCs using proximity-labeling proteomic approach. Moreover, we compared ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD036909 | Pride
Proximal proteome analysis Breast cancer Cancer stem cells Drug resistance Cd276 Lipid raft Protein-protein interaction Cd147 
ProteomicsDynamic interaction- and phosphoproteomics of CD147
Using affinity purification, mass spectrometry, and phospho-enrichment of isotope-labeled peptides, we examined the CD147 microenvironment and CD147-dependent signaling cascades in the Jurkat acute T cell leukemic cell line and its dynamics upon treatment with T cell stimulating agents.
ORGANISM(S): Homo sapiens (Human) 
2017-02-06 | PXD002055 | Pride
Human Cd147 
ProteomicsStrength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β2-adrenoceptor clusters assembled by alpha-actinin-4
Neisseria meningitidis (meningococcus) is an invasive bacterial pathogen that colonizes human vessels, causing thrombotic lesions and meningitis. Establishment of tight interactions with endothelial cells is crucial for meningococci to resist hemodynamic forces. Two endothelial receptors, CD147 and ...
ORGANISM(S): Homo sapiens (Human) 
2017-07-10 | PXD006212 | Pride
Basigin Endothelial cells Neisseria meningitidis Cd147 Nano-lc/ms/ms tandem mass spectrometry 
TranscriptomicsCD147 and downstream ADAMTSs promote the tumorigenesis of Kaposi sarcoma-associated herpesvirus
The Kaposi’s Sarcoma-associated Herpesvirus (KSHV) is the etiologic agent of several human cancers, including Kaposi’s Sarcoma (KS), which preferentially arise in immunocompromised patients but lack of effective therapeutic options. We have previously shown that KSHV or viral protein LANA can up...
ORGANISM(S): Homo sapiens 
2016-05-31 | E-GEOD-69067 | biostudies-arrayexpress
GenomicsCD147 drives keloid formation by promoting fibroblast proliferation via the CENPF signaling pathway
CD147 drives keloid formation by promoting fibroblast proliferation via the CENPF signaling pathway
PRJNA1399349 | ENA
TranscriptomicsCD147 drives keloid formation by promoting fibroblast proliferation via the CENPF signaling pathway
Keloids are benign dermal tumors, and keloid fibroblasts (KFs) play a critical role in their formation through hyperproliferation. However, the mechanism underlying this excessive fibroblast growth in keloids remains elusive. Here, we demonstrate that CD147 is upregulated in KFs and promotes their p...
ORGANISM(S): Homo sapiens 
2026-09-15 | GSE315810 | GEO
UnknownUbiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of glycoprotein CD147 intracellular trafficking.
Not available
S-EPMC9440431 | biostudies-literature
Genomics
Changes of gene expression between H460 cells overexpressed with CD147 and CD147-K234R
PRJNA636866 | ENA
Genomics
CD147-Th17 differentiation
PRJNA933282 | ENA
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