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ProteomicsA microRNA/circle RNA axis promotes metastasis through CDR1-mediated anoikis-resistance
Lung cancer is an intrinsically highly metastatic disease and the leading cause of cancer-related deaths worldwide. Although discovery of molecular aberrations in lung adenocarcinomas has led to development of effective targeted therapies, corresponding “drivers” in lung squamous carcinomas (LUSC) h...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD012286 | Pride
Human Cdr1 Lung Cancer Squamous 
ProteomicsGlaucoma-Associated CDR1 Peptide Promotes RGC Survival in Retinal Explants through Molecular Interaction with Acidic Leucine Rich Nuclear Phosphoprotein 32A (ANP32A)
Glaucoma is a complex, multifactorial optic neuropathy mainly characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, resulting in a decline of visual function. The pathogenic molecular mechanism of glaucoma is still not well understood, and therapeutic strategies spe...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2023-08-01 | PXD038373 | Pride
Glaucoma Neuroprotection Mass spectrometry Proteomics Anp32a 
GenomicsWhole genome sequencing of deletion strains of Candida albicans CDR1, CDR2, MDR1, CMP1, CNB1 and CRZ1 derived tebuconazole adaptors
From C. albicans reference strain SC5314, CDR1, CDR2, MDR1, CMP1, CNB1, CRZ1 were deleted. The deletion strains were spread on YPD plates supplemented with tebuconazole. Randomly 4 adaptors derived from each deletion strain were sequenced.
ORGANISM(S): Candida albicans 
2023-08-09 | E-MTAB-13238 | biostudies-arrayexpress
UnknownDysregulated miR-671-5p / CDR1-AS / CDR1 / VSNL1 axis is involved in glioblastoma multiforme.
Not available
S-EPMC4826240 | biostudies-literature
TranscriptomicsMutations in TAC1B drive increased CDR1 and MDR1 expression and azole resistance in Candida auris
Objective: Candida auris has emerged as a fungal pathogen of particular concern owing in part to its propensity to exhibit antifungal resistance, especially to the commonly prescribed antifungal fluconazole. In this work we aimed to determine how mutations in the transcription factor gene TAC1B, whi...
ORGANISM(S): Candidozyma auris 
2025-07-28 | GSE288372 | GEO
GenomicsMutations in TAC1B drive increased CDR1 and MDR1 expression and azole resistance in Candida auris
Mutations in TAC1B drive increased CDR1 and MDR1 expression and azole resistance in Candida auris
PRJNA1217042 | ENA
UnknownExpression of the onconeural protein CDR1 in cerebellum and ovarian cancer.
Not available
S-EPMC5963614 | biostudies-literature
TranscriptomicsThe Candida glabrata transcription factor Stb5p is a negative regulator of ATP-binding cassette transporters
The opportunistic yeast pathogen Candida glabrata is recognized for its ability to acquire resistance during prolonged treatment with azole antifungals. Resistance to azoles is largely mediated by the transcription factor PDR1, resulting in the upregulation of ATP-binding cassette (ABC) transporter ...
ORGANISM(S): Candida glabrata 
2013-03-11 | E-GEOD-37071 | biostudies-arrayexpress
UnknownDynamic regulation of Cdr1 kinase localization and phosphorylation during osmotic stress.
Not available
S-EPMC5682958 | biostudies-literature
UnknownFunctional analysis of Candida albicans Cdr1 through homologous and heterologous expression studies.
Not available
S-EPMC11974388 | biostudies-literature
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