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ProteomicsCE-MS Top Down Proteomics Multi-lab Study
A single gene can give rise to multiple functionally distinct forms of protein molecules, called proteoforms, originating from gene mutations, RNA alternative splicing, polymorphisms, and post-translational modifications (PTMs). It is essential to characterize proteins in a proteoform-specific manne...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-12-18 | PXD059108 | Pride
Ce-ms Top down proteomics Ce Ms 
ProteomicsOn-capillary cell lysis enables top-down proteomic analysis of single HeLa cells by CE-MS/MS
Proteomic analysis of limited samples and single cells requires specialized methods that prioritize high sensitivity and minimize sample loss. Consequently, sample preparation is one of the most important steps in limited sample analysis workflows to prevent sample loss. In this work, we have elimin...
ORGANISM(S): Homo sapiens (Human) 
2022-10-26 | PXD035339 | Pride
Top-down proteomics Single-cell top-down proteomics Tandem mass spectrometry Single-cell proteomics Capillary electrophoresis Ce-ms/ms 
MetabolomicsCE-MS Metabolomic and LC-MS Proteomic Analyses of Breast Cancer Exosomes Reveal Alterations in Purine and Carnitine Metabolism

A nano sheath-flow capillary electrophoresis mass spectrometry (CE-MS) system with electrospray ionization was used to profile cationic metabolite cargo in exosomes secreted by non-tumorigenic MCF-10A and tumorigenic MDA-MB-231 breast epithelial cells. CE-MS-based metabolomics revealed increased ...

2024-11-14 | MTBLS11190 | MetaboLights
UnknownCE-MS/MS and CE-timsTOF to separate and characterize intramolecular disulfide bridges of monoclonal antibody subunits and their application for the assessment of subunit reduction protocols.
Not available
S-EPMC10899284 | biostudies-literature
UnknownAugmented region of interest for untargeted metabolomics mass spectrometry (AriumMS) of multi-platform-based CE-MS and LC-MS data.
Not available
S-EPMC10287804 | biostudies-literature
UnknownOn-capillary Cell Lysis Enables Top-down Proteomic Analysis of Single Mammalian Cells by CE-MS/MS.
Not available
S-EPMC10118848 | biostudies-literature
ProteomicsZebrafish plasma analyzed by CE- and LC-MS/MS
Single analyses of a Zebrafish whole plasma digest were analyzed by both CE-MS/MS and LC-MS/MS. The identified peptides and their corresponding retention or migration times were used to train a 'blind' retention/migration time model using linear regression. This trained model provided us with inform...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2012-12-18 | PXD000112 | Pride
Danio rerio Ce-ms/ms Lc-ms/ms 
UnknownCE-MS with electrokinetic supercharging and application to determination of neurotransmitters.
Not available
S-EPMC6947659 | biostudies-literature
MetabolomicsFlow cytometry has a significant impact on the cellular metabolome (CE-MS assay)
The characterization of specialized cell subpopulations in a heterogeneous tissue is essential for understanding organ function in health and disease. A popular method of cell isolation is fluorescence-activated cell sorting (FACS) based on probes that bind surface or intracellular markers. In this ...
2018-11-06 | MTBLS633 | MetaboLights
ProteomicsCapillary electrophoresis coupled to electrospray ionization tandem mass spectrometry (CE-MS/MS) for ultra-sensitive proteomic analysis of limited sample
In this work, we developed an ultra-sensitive CE-MS/MS method for bottom-up proteomics analysis of limited samples, down to sub-nanogram levels of total protein. Analysis of 880 pg and 88 pg of HeLa protein digest standard by CE-MS/MS yielded ~1,100±46 and ~160±59 proteins, respectively, demonstrati...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027226 | Pride
Ultra-low flow liquid phase separation Ce-ms Ultra-sensitive proteomics Monolithic columns Capillary electrophoresis Rp-nlc-ms 
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