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ProteomicsMacrophages promote collagen fibrillogeneis through modulation of fibroblast circadian rhythms
Collagen deposition in fibroblasts, the primary collagen-producing cells, is regulated by both macrophages and the circadian rhythm, although how these regulatory processes interact with one another is unknown. Here, we reveal that macrophage-fibroblast interaction enhances collagen deposition which...
ORGANISM(S): Homo sapiens (Human) 
2026-08-07 | PXD061123 | Pride
Thp1 Circadian rhythm Polarisation Macrophages Collagen Secretome 
UnknownSNMP1 is critical for sensitive detection of the desert locust aromatic courtship inhibition pheromone phenylacetonitrile.
Not available
S-EPMC11229289 | biostudies-literature
MetabolomicsBranched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming

Macrophages are prominent immune cells in the tumor microenvironment that can be educated into pro-tumoral phenotype by tumor cells to favor tumor growth and metastasis. The mechanisms that mediate a mutualistic relationship between tumor cells and macrophages remain poorly characterized. Here, w...

2022-10-03 | MTBLS4497 | MetaboLights
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
ProteomicsIdentifying the interacting proteins of lignin biosynthetic P450 enzymes by affinity purification coupled with LC-MS/MS analysis
This project aims to identify the potential interacting proteins of lignin biosynthetic P450 enzymes by affinity purification and LC-MS/MS analysis. To this end, the genomic pieces of three lignin biosynthetic P450 genes C4H, C3’H and F5H were cloned into pMDCpC4H-HPB vector to generate HPB-fusion c...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-05-02 | PXD009033 | Pride
Lignin C3'h Affinity purification F5h C4h Lc-ms/ms 
MetabolomicsRapid UHPLC-MS metabolite profiling and phenotypic assays reveal genotypic impacts of nitrogen supplementation in oats
INTRODUCTION: Oats (Avena sativa L.) are a whole grain cereal recognised for their health benefits and which are cultivated largely in temperate regions providing both a source of food for humans and animals, as well as being used in cosmetics and as a potential treatment for a number of...
2020-06-11 | MTBLS804 | MetaboLights
UnknownEarly infancy dysbiosis in food protein-induced enterocolitis syndrome: A prospective cohort study.
Not available
S-EPMC10534226 | biostudies-literature
UnknownCharacteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer's disease.
Not available
S-EPMC6138637 | biostudies-literature
TranscriptomicsTranscription profiling of Corynebacterium glutamicum shows a differential response to moderate or severe heat shock of the HrcA- and HspR-dependent systems
Genome-wide transcription profiles analysis of the heat-shocked wild-type strain under moderate (40¡C) and severe heat stress (50¡C) revealed that a large number of genes are differentially expressed after heat shock. 358 genes were up-regulated and 420 were down-regulated in response to moderate he...
ORGANISM(S): Corynebacterium glutamicum 
2008-12-10 | E-MTAB-66 | biostudies-arrayexpress
UnknownMKP-1 is necessary for T cell activation and function.
Not available
S-EPMC2781480 | biostudies-literature
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