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TranscriptomicsTranscription profiling of wild type mouse lung after treatement with Bleomycin hydrogen chloride to examine disease progression in pulmonary fibrosis
Pulmonary fibrosis was induced by a single tail vein injection of Bleomycin hydrogen chloride (100 mg/kg body weight; 1/3 LD50; Nippon Kayaku Co. Ltd., Tokyo) to 6- to 8-wk-old mice. Mice (3-5/endpoint) were sacrificed 7, 15 and 23 days post Bleomycin administration and RNA samples were extracted fr...
ORGANISM(S): Mus musculus 
2008-03-06 | E-MUGN-1 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of human breast cancer MCF7 cells and clones thereof expressing human ERβ1 or ERβ2 upon treatment with antiestrogens and retinoids.
The aim of the experiment was to gain insight into the role of estrogen receptor beta (ERβ) isoforms in the response of breast cancer MCF7 cells to antiestrogens and retinoids. To this end, clones of MCF7 cells constitutively expressing human ERβ1 (MCF7-ERβ1) or ERβ2 (MCF7-ERβ2) were established and...
ORGANISM(S): Homo sapiens 
2022-12-13 | E-MTAB-12549 | biostudies-arrayexpress
UnknownA Computational Pipeline for the Extraction of Actionable Biological Information From NGS-Phage Display Experiments.
Not available
S-EPMC6769401 | biostudies-literature
UnknownRadiogenomic Analysis of F-18-Fluorodeoxyglucose Positron Emission Tomography and Gene Expression Data Elucidates the Epidemiological Complexity of Colorectal Cancer Landscape.
Not available
S-EPMC6374701 | biostudies-literature
ProteomicsA novel blood brain barrier-permeable IRE1 inhibitor prevents Glioblastoma relapse in mice
Inositol Requiring Enzyme 1 (IRE1) is a bifunctional serine/threonine kinase and endoribonuclease that is a major mediator of the Unfolded Protein Response (UPR) during endoplasmic reticulum (ER) stress. Tumor cells experience ER stress due to adverse environmental cues such as hypoxia or nutrient s...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD026908 | Pride
Ire1 Glioblastoma Unfolded protein response Inhibitors Endoplasmic reticulum 
GenomicsCo-activation of GR and NF-kB leads to extensive rearrangemnet of their binding sites and target genes
Global identification of activated GR and p65 binding sites and target genes using ChIP-seq in HeLa B2 cells. generation genome-wide chromatin state-maps of GR, p65 and RNAPII in HeLa B2 cells under conditions 1) DMSO (control); 2) TA 1M-BM-5M 4hr; 3) TNFM-NM-1 10ng/ml ; 4) TA 1M-BM-5M 4hr at at th...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-24518 | biostudies-arrayexpress
UnknownAnalysis of Prevalence and Risk Factors of Contact Sensitization with respect to the Occupational Profiles in a Greek Patient Cohort: A Retrospective Analysis of a Greek Referral Centre and Future Perspectives.
Not available
S-EPMC8121586 | biostudies-literature
UnknownA method of 2D/3D registration of a statistical mouse atlas with a planar X-ray projection and an optical photo.
Not available
S-EPMC3667217 | biostudies-literature
UnknownKEGGconverter: a tool for the in-silico modelling of metabolic networks of the KEGG Pathways database.
Not available
S-EPMC2764712 | biostudies-literature
UnknownA comparative genomic study in schizophrenic and in bipolar disorder patients, based on microarray expression profiling meta-analysis.
Not available
S-EPMC3608181 | biostudies-literature
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