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UnknownSingle nucleotide polymorphisms of nucleotide excision repair and homologous recombination repair pathways and their role in the risk of osteosarcoma.
Not available
S-EPMC4476324 | biostudies-literature
ProteomicsRhizobium leguminosarum glutathione peroxidase is essential for oxidative stress resistance and efficient nodulation
Glutathione plays a tremendous role in regulating the homeostasis of redox state, and appears to be essential for proper development of the root nodules. Glutathione peroxidase catalyzes the reduction of peroxides by oxidation of GSH to oxidized GSH (GSSG), which can in turn be reduced by glutathion...
ORGANISM(S): Rhizobium leguminosarum bv. viciae 
2020-11-16 | PXD022029 | Pride
Rhizobium leguminosarum  glutathione peroxidase  antioxidant function  symbiotic nitrogen fixation  quantitative proteomics 
ProteomicsProteomic and mutant analysis of hydrogenase gene hypE in symbiotic nitrogen fixation in Mesorhizobium huakuii
Hydrogenases catalyze the simple yet importantredox reaction between protons and electrons and H2, thus, mediate interactions between microorganisms and their chemical environment. A mutation in M. huakuii hypE gene was generated by homologous recombination. The hypE mutant grew a little faster than...
ORGANISM(S): Mesorhizobium huakuii 
2023-10-24 | PXD026564 | Pride
Mesorhizobium huakuii  fmoa  antioxidant  symbiotic nitrogen fixation  proteome & mesorhizobium huakuii  hydrogenases  hype gene  symbiotic nitrogen fixation  quantitative proteomics 
ProteomicsThe alterations of proteins expression related to insulin signaling pathway in the brain of phenobarbital addictive rats by TMT
Drug addiction is a chronic relapsing brain disease. The alterations of glucose uptake and metabolism were found in the brain of drug addicts. Insulin mediates brain glucose metabolism and its abnormality could induce brain injury and cognitive impairment. Here, we established a rat model of phenoba...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-10-29 | PXD021101 | Pride
Addiction Tmt Insulin signaling pathway Phenobarbital Proteomics 
ProteomicsMicroproteomics of PCBP2 biomolecular condensates
PCBP2 condensates were isolated by FAPS. To identify the PCBP2 condensates signature, we performed a mass spectrometry analysis and compared the pre-sorted and post-sorted fractions.For each sorting experiment, cells were cultured to approximately 80-90% confluence in three 15-cm dishes. Cells were ...
ORGANISM(S): Homo Sapiens 
2024-08-30 | PXD055459 |
ProteomicsFe(III) Mineral Encrustation Uncouples Respiration from Reproduction of the Nitrate-Reducing Fe(II)-Oxidizing bacterium Acidovorax sp. BoFeN1
Fe(II) can be oxidized by mixotrophic nitrate-reducing Fe(II)-oxidizing bacteria to Fe(III), leading to mineral precipitation. However, the effects of this process on the metabolism and reproduction ability of the Fe(II)-oxidizing bacterial cells have not yet been quantified. In this study, we inves...
ORGANISM(S): Acidovorax 
2026-01-01 | PXD072688 |
ProteomicsDIA quantitative proteomics of CENPM knockdown SW-13 cells
The project aims to detect the differential expression of proteomics in normal SW-13 cells and CENPM knockdown SW-13 cells
ORGANISM(S): Homo Sapiens 
2024-11-19 | PXD058018 |
MetabolomicsPKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis
Metabolic reprogramming is a hallmark of cancer. Herein we discover that the key glycolytic enzyme pyruvate kinase M2 isoform (PKM2), but not the related isoform PKM1, is methylated by co-activator-associated arginine methyltransferase 1 (CARM1). PKM2 methylation reversibly shifts the balance of met...
2021-07-30 | MTBLS533 | MetaboLights
ProteomicsIntegrated Proteogenomic Characterization of Medullary Thyroid Carcinoma
Global proteome data for 102 MTC samples, and phosphoproteome data for 74 MTC samples
ORGANISM(S): Homo Sapiens 
2022-04-01 | PXD032887 |
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