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TranscriptomicsPolysomal and total RNA in controls and after 10 min global brain ischemia and 8 hours of reperfusion
Complete global brain ischemia (CGBI) and reperfusion occur following resuscitation from cardiac arrest. Different brain neurons are selectively vulnerable to CGBI: pyramidal neurons of hippocampal CA3 survive 10 min CGBI but those of CA1 die at 3 days following 10 min CGBI. CA3 neurons are expecte...
ORGANISM(S): Rattus norvegicus 
2016-06-02 | E-GEOD-82146 | biostudies-arrayexpress
TranscriptomicsNitrate Stress in Desulfovibrio vulgaris Hildenborough
Using data from microarray experiments, we investigated the effects of excess sodium nitrate on Desulfovibrio vulgaris. Keywords: stress response, time course Comparison of cells treated with 105 mM sodium nitrate to untreated cells at times of 0, 30, 60, 120, and 240 min.
ORGANISM(S): Desulfovibrio vulgaris str. Hildenborough 
2010-06-22 | E-GEOD-20079 | biostudies-arrayexpress
MetabolomicsMetabolomic Responses of Arabidopsis Suspension Cells to Bicarbonate under Light and Dark Conditions
Global CO2 level presently recorded at 400 ppm is expected to reach 550 ppm in 2050, an increment likely to impact plant growth and productivity. Using targeted LC-MS and GC-MS platforms we quantified 229 and 29 metabolites, respectively in a time-course study to reveal short-term responses to diffe...
2017-04-25 | MTBLS311 | MetaboLights
TranscriptomicsPACAP dependency of genes regulated in adrenal gland
We investigated the effects of PACAP knock out on the transcriptosome profile of adrenal gland. A 35,546-clone mouse cDNA microarray was used to investigate transcriptional changes Keywords: transcript identification design In the hybridization method employed, equal amounts (2-5 ug/15.5 ul) of tota...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-7405 | biostudies-arrayexpress
Proteomicshuman Bora-interacting proteins
Mass spectrometry analysis of proteins associated with immunopurified Flag-Bora.
ORGANISM(S): Homo sapiens (Human) 
2025-09-08 | PXD066562 | Pride
Interaction Bora 
ProteomicsKlebsiella pneumoniae x546,ATCC15380, TMT
Klebsiella pneumoniae x546,ATCC15380, TMT,The samples were ground into a powder in liquid nitrogen. Then the powder was suspended in lysis buffer [1% sodium deoxycholate (SDS), 8M urea]. The mixture was allowed to settle at 4 鎺矯 for 30 min during which the sample were vortexed at every 5 min, and tr...
ORGANISM(S): Klebsiella pneumoniae subsp. pneumoniae DSM 30104 = JCM 1662 = NBRC 14940 Klebsiella pneumoniae Klebsiella pneumoniae MGH 78578 
2021-11-15 | PXD028396 | Pride
Atcc15380 Tmt Klebsiella pneumoniae x546 
MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
MetabolomicsJasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
Foliar stomatal movements are critical for regulating plant water loss and gas exchange. Elevated carbon dioxide (CO2) levels are known to induce stomatal closure. However, the current knowledge on CO2 signal transduction in stomatal guard cells is limited. Here we report metabolomic responses of Br...
2017-04-25 | MTBLS312 | MetaboLights
ProteomicsTRIM21 enhances bortezomib sensitivity in multiple myeloma by halting pro-survival autophagy
Bortezomib (bort) is an effective therapeutic agent for multiple myeloma (MM) patients; however, the majority of patients develop drug resistance. Autophagy, a highly conserved process that recycles cytosol or entire organelles via lysosomal activity, is essential for the survival, homeostasis and d...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042004 | Pride
Trim21 multiple myeloma bortezomib 
TranscriptomicsTranscription profiling of wild type and hog1 Candida albicans subjected to environmental stresses that are known to activate the Hog1 Stress-activated Protein Kinase
Based on studies in S. pombe (Chen et al., 2003), we predicted that conditions which activate C. albicans Hog1 would result in the induction of a common set of genes that are regulated by this SAPK (Smith et al., 2004). Hence in this study we compared the global transcriptional responses of wild-typ...
ORGANISM(S): Candida albicans 
2007-07-05 | E-MEXP-1134 | biostudies-arrayexpress
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