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MetabolomicsPKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis
Metabolic reprogramming is a hallmark of cancer. Herein we discover that the key glycolytic enzyme pyruvate kinase M2 isoform (PKM2), but not the related isoform PKM1, is methylated by co-activator-associated arginine methyltransferase 1 (CARM1). PKM2 methylation reversibly shifts the balance of met...
2021-07-30 | MTBLS533 | MetaboLights
UnknownImpact of mineral oil overlay on immature oocyte maturation in an optimized in vitro culture system.
Not available
S-EPMC12934039 | biostudies-literature
UnknownMolecular characterization, purification, and antioxidant activity of recombinant superoxide dismutase from the Pacific abalone Haliotis discus hannai Ino.
Not available
S-EPMC7359182 | biostudies-literature
UnknownMETTL4-mediated nuclear N6-deoxyadenosine methylation promotes metastasis through activating multiple metastasis-inducing targets.
Not available
S-EPMC9716733 | biostudies-literature
ProteomicsProteomic profiling of rice (Oryza sativa Nipponbare) roots during compatible interaction with the root-knot nematode Meloidogyne graminicola
This study employed label-free quantitative mass spectrometry to investigate the proteomic changes in roots of the susceptible rice cultivar Nipponbare during a compatible interaction with the root-knot nematode Meloidogyne graminicola. Root samples were collected at four time points: before inocula...
ORGANISM(S): Oryza sativa (Rice) 
2025-12-08 | PXD071707 | Pride
Meloidogyne graminicola Plant-pathogen interaction. Label-free quantitative proteomics Compatible interaction Nipponbare Root proteome Rice 
ProteomicsSuccinylation proteome analysis of Cd-exposed Neuro-2a cells
Cadmium is a neurotoxic compound which induces cognitive alterations similar to those produced by Alzheimer's disease (AD). Autophagic flux impairment is a hallmark in Cd-induced AD-like pathology. However, the underlying mechanism remains obscure. In these study, Neuro-2a cells were exposed to diff...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD048158 | Pride
Succinylation proteome analysis  cd  neuro-2a cells 
ProteomicsProfiling of the detergent-insoluble proteome of the cortical brain tissues by TMT-LC/LC-MS/MS
Mass spectrometry analysis of insoluble proteome from 5xFAD/Mdk-KO mouse brain. This study examines the insoluble protein fraction, focusing on aggregation-prone proteins including Aβ and its associated proteins. The data reveals significant accumulation of Aβ-correlated proteins and microglial comp...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-16 | PXD061104 | Pride
Tmt-lc/lc-ms/ms Ad Mdk Mouse Detergent-insoluble 
MetabolomicsPlot diversity differentially affects the chemical composition of leaves, roots and root exudates in four subtropical tree species

Plants produce thousands of compounds, collectively called the metabolome, which mediate interactions with other organisms. The metabolome of an individual plant may change according to the number and nature of these interactions. We tested the hypothesis that tree diversity level affects the met...

2021-08-09 | MTBLS1968 | MetaboLights
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
UnknownObservation of charge-parity symmetry breaking in baryon decays.
Not available
S-EPMC12310544 | biostudies-literature
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