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MetabolomicsExtracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
The accumulation of acidic metabolic waste products within the tumor microenvironment profoundly inhibits effector functions of tumor-infiltrating lymphocytes (TILs). However, it is unclear whether extracellular-acidosis impacts T cell metabolic fitness and differentiation status. Here, we surprisin...
2023-01-17 | MTBLS6661 | MetaboLights
UnknownExperimental infection of Z:ZCLA Mongolian gerbils with human hepatitis E virus.
Not available
S-EPMC4299338 | biostudies-literature
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
UnknownSingle-cell RNA sequencing depicts the local cell landscape in thyroid-associated ophthalmopathy.
Not available
S-EPMC9418739 | biostudies-literature
ProteomicsThe phosphoproteomic responses of duck (Cairna moschata) to classical/novel duck reovirus infections in the spleen tissue
Duck reovirus (DRV) is a fatal member of the genus Orthoreovirus in the family Reoviridae. The disease caused by DRV leads to huge economic losses to the duck industry. Post-translational modification is an efficient strategy to enhance the immune responses to virus infection. However, the roles of ...
ORGANISM(S): Cairina moschata 
2021-09-09 | PXD016423 | Pride
Duck reovirus  immune response  pattern-recognition receptors  phosphorylation  post-translational modification 
ProteomicsComparative proteomic analysis revealed the differential responses to novel duck reovirus infection in the bursa of Fabricius of Cairna moschata
Duck reovirus (DRV) is well-studied aquatic bird virus belonging to the Orthoreovirus genus of the Reoviridae family. The bursa of Fabricius is an immunologically organ against virus invasion. However, the responses of the bursa of Fabricius of Cairna moschata to DRV infection are largely unknown. T...
ORGANISM(S): Cairina moschata 
2022-08-12 | PXD025093 | Pride
Cairna moschata  differential accumulated protein  reovirus  proteomic analysis  the bursa of fabricius 
ProteomicsProteomics insights into the molecular mechanisms of c9, t11-CLA synthesis
Cis-9, trans-11-conjugated linoleic acid (c9, t11-CLA), a functional fatty acid, is one of the research hotspots in the fields of functional dairy products development because of its multiple beneficial effects in humans and animals. In milk, most c9, t11-CLA is de novo synthesized from trans-11-oct...
ORGANISM(S): Bos taurus (Bovine) 
2022-08-12 | PXD028620 | Pride
Cis-9 Trans-11-conjugated linoleic acid  stearoyl-coa desaturase 1  mac-t cells  proteomics  functional fatty acid 
UnknownSuppression of colorectal tumorigenesis by recombinant Bacteroides fragilis enterotoxin-2 in vivo.
Not available
S-EPMC5292333 | biostudies-literature
Unknown<i>Lycorine hydrochloride</i> Suppresses the Proliferation and Invasion of Esophageal Cancer by Targeting TRIM22 and Inhibiting the JAK2/STAT3 and Erk Pathways.
Not available
S-EPMC11898953 | biostudies-literature
UnknownExcessive Substitution of Fish Meal with Fermented Soybean Meal Induces Oxidative Stress by Impairing Glutathione Metabolism in Largemouth Bass (Micropterus salmoides).
Not available
S-EPMC10740881 | biostudies-literature
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