Sort   by:  
 Page size 
TranscriptomicsCis- and trans- regulatory divergence between progenitor species determines gene-expression novelty in Arabidopsis allopolyploids
Gene-expression divergence between species shapes morphological evolution, but the molecular basis is largely unknown. Here we show cis- and trans-regulatory elements and chromatin modifications on gene-expression diversity in genetically tractable Arabidopsis allotetraploids. In Arabidopsis thalian...
ORGANISM(S): Arabidopsis arenosa x Arabidopsis thaliana 
2012-05-31 | E-GEOD-29687 | biostudies-arrayexpress
ProteomicsDIA-MS Detect the Dephosphorylation of Tau by Phosphorylation Targeting Chimera (PhosTAC)
Microtubule-associated protein tau is essential for microtubule assembly and stabilization. Hyperphosphorylation of the microtubule-associated protein tau plays an important pathological role in the development of Alzheimer’s disease and other tauopathies, one of the greatest unmet demands in the cl...
ORGANISM(S): Homo sapiens (Human) 
2023-03-16 | PXD037459 | Pride
Dephosphorylation Dia-ms Tau Phostac Phosphoproteomics 
ProteomicsDIA-MS Detect the Targeted EGFR Dephosphorylation by Phosphorylation Targeting Chimera (PhosTAC)
Epidermal growth factor receptor (EGFR) is an important receptor tyrosine kinase protein. Activated EGFR promotes downstream signal transductions through phosphorylation, and its phosphorylation has been implicated in pathologies including many types of cancers. Previously, our lab has developed the...
ORGANISM(S): Homo sapiens (Human) 
2024-04-02 | PXD038022 | Pride
Phosphoproteomics Dia-ms Phostac Egfr Kinase 
ProteomicsProteomic analysis of the physiological E3 ubiquitin ligase responsible for PIN1 degradation
Induced oncoproteins degradation provides an attractive anti-cancer modality. Activation of anaphase-promoting complex (APC/CCDH1) prevents cell cycle entry by targeting crucial mitotic proteins for degradation. Phosphorylation of its co-activator CDH1 modulates the E3 ligase activity, but little is...
ORGANISM(S): Homo sapiens (Human) 
2024-02-28 | PXD046325 | Pride
Pin1 Proteomics Cdh1 
ProteomicsLSDV012 interacts with IFIT1/5 coip data
LSDV012 interacts with IFIT1/5 Co-Immunoprecipitationdata
ORGANISM(S): Bos Taurus 
2024-09-26 | PXD056306 |
ProteomicsBioactive components of Mongolian medicinal Gentiana dahurica Fisch. flowers inhibit the NF-κB signaling pathway and ameliorate chronic obstructive pulmonary disease
Bioactive components of Mongolian medicinal Gentiana dahurica Fisch. flowers inhibit the NF-κB signaling pathway and ameliorate chronic obstructive pulmonary disease
ORGANISM(S): Mus Musculus 
2026-04-08 | PXD076741 |
Sort   by:  
 Page size