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ModelsWei2011_MLCactivationPathway_EndothelialPermeability
This model is from the article: An Integrated Mathematical Model of Thrombin-, Histamine-and VEGF-Mediated Signalling in Endothelial Permeability. Wei X, Han B, Zhang J, Liu X, Tan C, Jiang Y, Low B, Tidor B, Chen Y. BMC Syst Biol. 2011 Jul 15;5:112. ...
2005-01-01 | MODEL1102210000 | BioModels
TranscriptomicsExpression analysis of Tim-3 knockdown RAW264.7 cell
Investigation of whole genome gene expression level changes in a Tim-3 knockdown RAW264.7 cell, compared to control siRNA transfected RAW264.7 cell. The Tim-3 knockdown of this cell render it hyper-reactive to TLR stimulation. Tim-3 knockdown analyzed in this study are further described in Li Y, Fen...
ORGANISM(S): Mus musculus 
2012-12-05 | E-GEOD-42729 | biostudies-arrayexpress
Proteomicshuman plasma sample parallel reaction monitoring
Women are vulnerable to cervical diseases including normal control, HSIL and early stage cervical carcinoma . The parallel reaction monitoring mass spectrometry (PRM-MS) were used to qualitatively and quantitatively analyze the candidate differential proteins identified in our previous studies and t...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD022756 | Pride
Cervical cancer 
GenomicsGenome-wide survey of YY1 targets in C2C12 cells by High-throughput sequencing
By applying ChIP-seq, we generated genome-wide maps of YY1 in skeletal myoblasts and myotubes. We found that YY1 binds to 1820 confident target with a large portion residing in the intergenic regions. In addition, YY1 was found to activate many loci, and there is no significant overlap between YY1 a...
ORGANISM(S): Mus musculus 
2013-08-15 | E-GEOD-45875 | biostudies-arrayexpress
MetabolomicsThe Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis

BACKGROUND: Manchurian walnut (Juglans mandshurica Maxim.) is a tree with multiple industrial uses and medicinal properties in the Juglandaceae family (walnuts and hickories). J. mandshurica produces juglone, which is a toxic allelopathic agent and has potential utilization value...

2022-05-18 | MTBLS3657 | MetaboLights
ProteomicsTranscriptomic and Proteomic Profiling of Piroplasmosis Resistance in Yunnan Humped Cattle
This project investigates the genetic basis of piroplasmosis resistance in Yunnan humped cattle through integrated transcriptomic and proteomic analyses to identify candidate genes and proteins. Proteomics datasets included the following: (1) Lancang samples: Fe16CXN_QC1--Fe16CXN_QC3(Quality testing...
ORGANISM(S): Bos Taurus Bos Indicus 
2026-04-03 | PXD076555 |
ProteomicsSuccinyl-CoA synthetase deficiency in mouse forebrain results in hyper-succinylation with perturbed neuronal transcriptional regulation and metabolism
Lysine-succinylation is a subtype of protein acylation associated with metabolic regulation of succinyl-CoA in the TCA cycle. Deficiency of succinyl-CoA synthetase (SCS), the TCA-cycle enzyme catalyzing the reversible conversion of succinyl-CoA to succinate, leads to mitochondrial encephalomyopathy ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-06-21 | MSV000089697 | MassIVE
Proteomicsidentification of MACC1-AS1 binding proteins
In vitro RNA synthesis and pull-down assay and MS spectrometry
ORGANISM(S): Homo Sapiens 
2019-07-12 | PXD014601 |
ProteomicsProteomic analysis of rG4_A selectively degraded proteins through the proteasome
To explore the effects of rG4-PROTACs on the whole proteome, Hela cells were treated with blank (empty transfection control), rG4 mut_A, rG4_A, or rG4_A plus MG132, and a proteomic analysis was included in the subproject
ORGANISM(S): Homo Sapiens 
2024-11-21 | PXD058113 |
ProteomicsArginine methylation of METTL14 promotes RNA N6-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells
m6A is the most abundant modification of mRNA in mammals and plays an important role in human development and disease. METTL14 is a key component of m6A methyltransferase complex. The project showed that its post-translational arginine methylation can regulate the generation of m6A and the endoderm ...
ORGANISM(S): Homo Sapiens 
2021-05-17 | PXD018458 |
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