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UnknownChanges in Rumen Microbiota Affect Metabolites, Immune Responses and Antioxidant Enzyme Activities of Sheep under Cold Stimulation.
Not available
S-EPMC7999998 | biostudies-literature
ProteomicsComparative Phosphoproteomic Profiling of Type III Adenylyl Cyclase Knockout and Control, Male and Female Mice Prefrontal Cortex
Type III adenylyl cyclase (AC3, ADCY3) is predominantly enriched in neuronal primary cilia throughout the central nervous system (CNS). Genome-wide association studies in humans have associated ADCY3 with major depressive disorder and autistic spectrum disorder, both of which exhibit sexual dimorphi...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-10 | PXD012259 | Pride
Phosphoproteomics Mouse Adcy3 Gender-biased 
ProteomicsDUSP2 dephosphorylates STAT3 at Y705 and S727 residues
In the related study, to determine whether DUSP2 definitively served as a phosphatase for STAT3, an in vitro phosphatase assay was used. Using S-tag beads, p-STAT3 was pulled down from IL-6 stimulated HEK293T cells transfected with STAT3-S-Tag. DUSP2 or control protein, which was purified from HEK29...
ORGANISM(S): Homo sapiens (Human) 
2015-10-13 | PXD002743 | Pride
Dusp2 Phosphorylation Stat3 
ProteomicsLC-MS/MS analysis of B12 treated SH-SY5Y cells
B12 is a compound that has neuroprotective effects. We investigated the protein expression profile associated with the neuroprotective effects of B12 on human neuronal cells SH-SY5Y using label-free quantitative proteomics.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-12-29 | MSV000079437 | MassIVE
TranscriptomicsmRNA regulation in normal or TNF-a/IL-4-activated bronchial epithelial cells (BEAS-2B)
Illumina microarray experiment on BEAS-2B cells. Cells were seeded 24 h before TNF-a/IL-4 (50 ng/ml) treatment that lasted for 18 h. Cytoplasmic RNA of both normal and activated BEAS-2B cells were collected for microarray. Cells were seeded 24 h before TNF-a/IL-4 (50 ng/ml) treatment that lasted f...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-13119 | biostudies-arrayexpress
UnknownPeptides based on the interface of hnRNPA2B1-transthyretin complex repress retinal angiogenesis in diabetic retinopathy.
Not available
S-EPMC12008863 | biostudies-literature
ProteomicsSTN1 facilitates metastasis by promoting transcription of EMT-activator ZEB1 in pancreatic cancer
As pancreatic ductal adenocarcinoma (PDAC) poses a formidable clinical challenge, demanding further exploration of its pathogenesis and drugs targeted for metastasis-the main cause of mortality. Here, we identified STN1, a CST complex member crucial for maintaining telomere lengths and genome stabil...
ORGANISM(S): Homo sapiens (Human) 
2025-08-05 | PXD062518 | Pride
Pancreatic cancer  stn1  stat3 
ProteomicsDeep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression
The molecular networks underlying Alzheimer’s disease (AD) are not well-defined. We present temporal profiling of >14,000 proteins and >34,000 phosphosites at the asymptomatic and symptomatic stages of AD, deep proteomics analysis of transgenic mouse models.
ORGANISM(S): Mus musculus (Mouse) 
2020-04-16 | PXD018590 | Pride
Tmt-lc/lc-ms/ms Brain Ad mouse model 
UnknownInhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein.
Not available
S-EPMC8845813 | biostudies-literature
ProteomicsSecretome Comparison of Mesenchymal Stromal Cells and Immature Osteoblasts
Osteoblasts are a key component of the endosteal hematopoietic stem cell (HSC) niche and have long been recognized with strong hematopoietic supporting activity. Osteoblast conditioned media (OCM) enhances the growth of hematopoietic progenitors in culture and modulate their engraftment activity. We...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-15 | MSV000088384 | MassIVE
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