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ProteomicsNuclear Paxillin Modulates Alternative Splicing Programs in Neurons during Sensitive Periods of Brain Development
During sensitive postnatal periods, brain neural circuits undergo significant refinement coincident with widespread neuronal alternative splicing events in which hundreds of genes alter their splice site selection to generate isoforms essential for synaptic plasticity. Here, we reveal that neuronal ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-08-08 | PXD060131 | Pride
Neuron Brain Rat Cortex Paxillin Alternative splicing 
UnknownComparative Transcriptomic Analyses for the Optimization of Thawing Regimes during Conventional Cryopreservation of Mature and Immature Human Testicular Tissue.
Not available
S-EPMC10778995 | biostudies-literature
UnknownRNA Transcripts in Human Ovarian Cells: Two-Time Cryopreservation Does Not Affect Developmental Potential.
Not available
S-EPMC10139221 | biostudies-literature
ProteomicsTailoring an Intravenously Injectable Oncolytic Virus for Augmenting Radiotherapy
Oncolytic viruses (OVs) combined with radiotherapy (RT) have shown promise in clinical trials but remain limited by unsatisfactory efficacy. Key challenges include poor intravenous delivery, insufficient RT-induced DNA damage, and suboptimal anti-tumor immune responses. Herein, we developed a novel ...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-02-02 | PXD060493 |
UnknownInherited NUDT15 variant is a genetic determinant of mercaptopurine intolerance in children with acute lymphoblastic leukemia.
Not available
S-EPMC4375304 | biostudies-literature
UnknownUtility of early screening magnetic resonance imaging for extensive hip osteonecrosis in pediatric patients treated with glucocorticoids.
Not available
S-EPMC4322260 | biostudies-literature
UnknownClinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia.
Not available
S-EPMC4962704 | biostudies-literature
UnknownSynthesis of Self-Assembled Multifunctional Nanocomposite Catalysts with Highly Stabilized Reactivity and Magnetic Recyclability.
Not available
S-EPMC4857104 | biostudies-literature
UnknownAqueous Phase Synthesis of Cu2-x S Nanostructures and Their Photothermal Generation Study.
Not available
S-EPMC6740407 | biostudies-literature
ProteomicsTo identify the nuclear partner(s) of TYRO3 in colon cells using LC-Quadrupole Time-of-Flight Mass Spectrometry.
Colorectal cancer (CRC) is one of the most common death-related cancers worldwide. Aberrant expression of oncogenes is regarded as a predominant factor in CRC development. In our study, we found that TYRO3 intracellular domain nuclear translocation promotes CRC cell proliferation, metastasis, and tu...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD029743 | Pride
Tyro3 Lc-quadrupole time-of-flight mass spectrometry Human Colon 
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