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UnknownProtein phosphatase 4 promotes Hedgehog signaling through dephosphorylation of Suppressor of fused.
Not available
S-EPMC7442787 | biostudies-literature
UnknownAMPK attenuates SHH subgroup medulloblastoma growth and metastasis by inhibiting NF-κB activation.
Not available
S-EPMC9867863 | biostudies-literature
MetabolomicsMulti-omics insights into high-carotenoid hybrid potato lines: enhanced nutritional quality and metabolic regulation for food applications

Modern potato varieties often exhibit low carotenoid content, limiting their nutritional value and processing performance. This study employed a multi-omics approach (physicochemical analysis, metabolomics, mineral profiling, transcriptomics, and microbiome sequencing) to investigate the molecula...

2025-11-12 | MTBLS13298 | MetaboLights
ProteomicsIdentification of Small Open Reading Frame-encoded Peptides in Glioma by an Optimized Proteomics Strategy
Small open reading frame-encoded peptides (SEPs) are peptides or proteins encoded by previously unannotated sequences in the genome. Although ribosome profiling and bioinformatics could predict a large number of SEPs, mass spectrometry (MS) is the only direct method for their identification. However...
ORGANISM(S): Homo Sapiens 
PXD058073 |
ProteomicsSOCS5-RBMX stimulates SREBP1-mediated lipogenesis to promote metastasis in HCC
SOCS5 stimulate the promoter of SREBP1 to induce de novo lipogenesis to promote HCC metastasis
ORGANISM(S): Homo Sapiens 
2024-01-22 | PXD048740 |
ProteomicsHistone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting
To look for factors that may have preferential binding to H3S28ph and mediate the stimulation to gene expression.
ORGANISM(S): Mus Musculus 
2022-05-25 | PXD034125 |
ProteomicsThe Glomerulus Multi-Omics Analysis Provides Deeper Insights into Diabetic Nephropathy
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), however, the detail mechanisms remain unclear. Here, we integrated the transcriptomics and proteomics profiles of glomeruli isolated from 50 biopsy-proven DN patients and 25 controls to explore the new discoveries unde...
ORGANISM(S): Homo Sapiens 
2023-03-06 | PXD040617 |
ProteomicsUrine proteomics in primary antiphospholipid syndrome
In this study, using proteomics study of urine samples from patients with primary APS (PAPS) and healthy controls (HC), we identified several proteins that discriminated Obstetric APS (OAPS) and Thrombotic APS (TAPS) from each other, as well as from HC.
ORGANISM(S): Homo Sapiens 
PXD027694 |
ProteomicsAnalysis of protein interaction between human platelets and SARS-CoV-2 envelope protein
Analysis of protein interaction between platelets and SARS-CoV-2 envelope protein
ORGANISM(S): Homo Sapiens Severe Acute Respiratory Syndrome Coronavirus 2 
2023-08-08 | PXD037073 |
ProteomicsDPHL v2: An updated and comprehensive DIA pan-human assay library for quantifying more than 14,000 proteins
we generated DPHL v2 from 1608 DDA-MS data acquired using Orbitrap mass spectrometers. The data included 586 DDA-MS newly acquired from 17 tissue types, while 1022 files were derived from DPHL v1. DPHL v2 thus comprises data from 24 sample types, including several cancer types . We generated four va...
ORGANISM(S): Homo Sapiens 
2023-01-18 | PXD039313 |
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