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TranscriptomicsEarly gene expression after YF17D vaccination that is associated with YF17D-specific T cell responses
This study investigates the post-vaccination gene expression associated with T cell response and why humoral immunity does not inform cellular responses post-vaccination. The experiment is the transcriptional profiling of peripheral blood mononuclear cells (PBMCs) from 12 subjects collected at day 0...
ORGANISM(S): Homo sapiens 
2026-04-14 | E-MTAB-15199 | biostudies-arrayexpress
TranscriptomicsEarly gene expression after COVID-19 mRNA (BNT162b2) vaccination that is associated with spike-specific T cell responses
This study investigates the post-vaccination gene expression associated with T cell response and why humoral immunity does not inform cellular responses post-vaccination. The experiment is the transcriptional profiling of peripheral blood mononuclear cells (PBMCs) from 21/27 subjects collected at da...
ORGANISM(S): Homo sapiens 
2026-04-21 | E-MTAB-15195 | biostudies-arrayexpress
TranscriptomicsDefining CD4 T Cell Memory by the Epigenetic Landscape of CpG DNA Methylation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-01-20 | E-GEOD-59860 | biostudies-arrayexpress
GenomicsDefining CD4 T Cell Memory by the Epigenetic Landscape of CpG DNA Methylation [Bisulfite-Seq]
Memory T cells are primed for rapid responses to antigen; however, the molecular mechanisms responsible for priming remain incompletely defined. CpG methylation in promoters is an epigenetic modification, which regulates gene transcription. Using targeted bisulfite sequencing, we examined methylatio...
ORGANISM(S): Homo sapiens 
2015-01-20 | E-GEOD-59858 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNAseq and scTCRseq of human CD8 T cells from blood and skin compartments in Dengue patients
Using a skin-blister induction model established for dengue, we investigated the transcriptional signatures and TCR repertoire of matched CD8 T cells in skin and blood samples
ORGANISM(S): Homo sapiens 
2026-04-14 | E-MTAB-16332 | biostudies-arrayexpress
TranscriptomicsDefining CD4 T Cell Memory by the Epigenetic Landscape of CpG DNA Methylation [RNA-Seq]
Memory T cells are primed for rapid responses to antigen; however, the molecular mechanisms responsible for priming remain incompletely defined. CpG methylation in promoters is an epigenetic modification, which regulates gene transcription. Using targeted bisulfite sequencing, we examined methylatio...
ORGANISM(S): Homo sapiens 
2015-01-20 | E-GEOD-59846 | biostudies-arrayexpress
ProteomicsEukaryotic catecholamine hormones influence the chemotactic control of Vibrio campbellii by binding to the coupling protein CheW
In addition to their well-known role as stress-associated catecholamine hormones in animals and humans, epinephrine (EPI) and norepinephrine (NE) act as interkingdom signals between eukaryotic hosts and bacteria. However, the molecular basis of their effects on bacteria is not well understood. In in...
ORGANISM(S): Vibrio campbellii (strain ATCC BAA-1116 / BB120) Bacteria 
2022-04-04 | PXD029119 | Pride
Q exactive plus Epinephrine Phenylephrine V. campbellii Orbitrap fusion 
TranscriptomicsDefining CD4 T Cell Memory by the Epigenetic Landscape of CpG DNA Methylation [Affymetrix]
Memory T cells are primed for rapid responses to antigen; however, the molecular mechanisms responsible for priming remain incompletely defined. CpG methylation in promoters is an epigenetic modification, which regulates gene transcription. Using targeted bisulfite sequencing, we examined methylatio...
ORGANISM(S): Homo sapiens 
2015-01-20 | E-GEOD-58684 | biostudies-arrayexpress
TranscriptomicsGene expression changes in older adults post-Shingrix vaccination
This study investigates the post-vaccination gene expression associated with protective T cell levels and why it takes two doses to boost an anamnestic response in older adults using the AS01b-adjuvanted recombinant zoster vaccine (RZV, ShingrixTM). The experiment is the transcriptional profiling of...
ORGANISM(S): Homo sapiens 
2025-07-07 | E-MTAB-14708 | biostudies-arrayexpress
UnknownHomology modeling of the CheW coupling protein of the chemotaxis signaling complex.
Not available
S-EPMC3737408 | biostudies-literature
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