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The transgenerational effects of pesticide chlordecone on prostate
Histone mark modifications in murine ovary after gestational exposure to chlordecone
RNA seq project designed to understand the role of pesticide on transription of mRNA in the testis. We treated adult female mice with chlordecone with doses 0 (control), 100 Xg/kg/day and 1 mg/kg/day during gestation period E6- E15. Male born from Chlordecone- treated mice were crossed for a three g...
ORGANISM(S): Mus musculus 
2018-07-10 | GSE86438 | GEO
Transgenerational effect of Chlordecone
Chlordecone (CLD) is a pesticide used to control the banana weevill in the French West Indies from 1970 to 1993. Despite its ban in the 90s, the highly persistence of CLD and contamination of the food webs raised tremendous concern for public health [1]. CLD can induce reprotoxic, neurotoxic and hep...
ORGANISM(S): Homo sapiens (Human) 
2025-06-10 | PXD043683 | Pride
Chlordecone (CLD) is a pesticide used to control the banana weevill in the French West Indies from 1970 to 1993. Despite its ban in the 90s, the highly persistence of CLD and contamination of the food webs raised tremendous concern for public health [1]. CLD can induce reprotoxic, neurotoxic and hep...
ORGANISM(S): Homo sapiens (Human) 
2025-06-10 | PXD043763 | Pride
We hypothesized that gestational exposure to chlordecone can lead to alteration of murine ovary's epigenetic landscape. To test our hypothesis, we exposed mice to chlordecone during embryonic development and we analyzed F1 female progeny epigenetic mark H3K4me3 in ovaries. We performed ChIP using an...
ORGANISM(S): Mus musculus 
2019-05-21 | GSE129897 | GEO
Genomics
Chlordecone biotransformation study
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