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ProteomicsSWATH-MS insights on butyric acid effect on mAbs production and redox homeostasis in CHO cells.
Sodium butyrate (NaBu) is well-known for its capacity to hinder cellular growth and act as a histone deacetylase inhibitor. It is commonly employed in the cultivation of recombinant Chinese hamster ovary (CHO) cell cultures to boost the production of specific proteins, such as antibodies. In this in...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2025-05-06 | PXD048575 | Pride
Lc-msms Redox Swath-ms Cho cells Mabs production Butyric acid 
TranscriptomicsDistinct Sets of Genetic Alterations in Melanoma
We compared genome-wide DNA copy number alterations and mutational status in BRAF and RAS genes of 126 primary melanomas arising in four groups in which UV exposure differ: skin with (n=30), and without chronic sun damage (n=40); palms, soles and subungual (acral) sites (n=36) (which have very littl...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-2631 | biostudies-arrayexpress
TranscriptomicsExpression data from malignant human B-cell cell lines
We used global gene expression profiles from human B-cell cell lines to generate gene expression signatures for prediction of response to the drugs cyclophosphamide, doxorubicin or vincristine. The signatures were validated in two publicly available clinical cohorts. Global gene expression data comb...
ORGANISM(S): Homo sapiens 
2015-04-19 | E-GEOD-53798 | biostudies-arrayexpress
UnknownLiver disease-associated keratin 8 and 18 mutations modulate keratin acetylation and methylation.
Not available
S-EPMC6988862 | biostudies-literature
TranscriptomicsThe transcription factor Amr1 induces melanin biosynthesis and suppresses virulence in Alternaria brassicicola
Alternaria brassicicola is a successful saprophyte and necrotrophic plant pathogen. Several A. brassicicola genes have been characterized as virulence factors affecting pathogenesis of Brassica species. To study regulatory mechanisms of pathogenesis, we mined 421 genes in silico encoding putative ...
ORGANISM(S): Alternaria brassicicola 
2013-02-19 | E-GEOD-36781 | biostudies-arrayexpress
ModelsKim2007 - Crosstalk between Wnt and ERK pathways
Kim2007 - Crosstalk between Wnt and ERK pathways Experimental studies have shown that both Wnt and the MAPK pathways are involved in the pathogenesis of various kinds of cancers (eg. colorectal cancer). The crosstalk between the two pathways have also been identified. Here, Kim et ...
2024-09-02 | BIOMD0000000149 | BioModels
UnknownProminent expression of sialyl Lewis X-capped core 2-branched O-glycans on high endothelial venule-like vessels in gastric MALT lymphoma.
Not available
S-EPMC3076943 | biostudies-literature
UnknownThe ANGUSTIFOLIA gene of Arabidopsis, a plant CtBP gene, regulates leaf-cell expansion, the arrangement of cortical microtubules in leaf cells and expression of a gene involved in cell-wall formation.
Not available
S-EPMC125914 | biostudies-literature
TranscriptomicsAtf1-mediated active gene response to H2O2 challenge.
Here we present the study on ChIP-chip mapping of the genomic binding sites for Sty1, Atf1, and the Atf1's binding partner Pcr1; the genome-wide transcriptional profiling of the atf1 and pcr1 strains in response to H2O2; and the phenotypic assessment of ~90 Atf1/Pcr1-bound or unbound genes for growt...
ORGANISM(S): Schizosaccharomyces pombe 
2010-07-19 | E-GEOD-13053 | biostudies-arrayexpress
UnknownPredicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models.
Not available
S-EPMC4396063 | biostudies-literature
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