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Non-coding regions of the genome contain cis-regulatory elements (CREs) that govern transcriptional activity critical for development and physiologic functions of major metabolic tissues, such as islets, adipose, liver, and skeletal muscle. Moreover, they contain the majority of genetic variants ass...
ORGANISM(S): Mus musculus 
2023-12-31 | GSE210138 | GEO
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003152 | Pride
Genetic alterations that activate protein kinase A (PKA) signaling are found across many tumor types, but their downstream oncogenic mechanisms are poorly understood. We used global phosphoproteomics and kinome activity profiling to map the conserved signaling outputs driven by diverse genetic chang...
ORGANISM(S): Homo sapiens (Human) 
2023-02-09 | PXD025508 | Pride
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