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UnknownNivolumab Monotherapy for First-Line Treatment of Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC5569692 | biostudies-literature
TranscriptomicsGenome wide gene expression during lung development in three inbred mouse strains
To better understand the temporal dynamics of gene expression during normal murine lung development we characterized global gene expression at 26 time points in three common inbred strains of mice (A/J, C57BL/6J, and C3H/HeJ). The data set provides a unique resource for identifying patterns of gene ...
ORGANISM(S): Mus musculus 
2016-07-01 | E-GEOD-74243 | biostudies-arrayexpress
UnknownCharacterization of lung inflammation and its impact on macrophage function in aging.
Not available
S-EPMC4632167 | biostudies-literature
TranscriptomicsGene profiling of heart atria in PI3K and Mst1 mouse models
We used microarrays to detail genome-wide gene expression underlying cardiac myocyte pathologies and identified candidate genes and specific pathways affecting cardiac myopathies Keywords: transgenics, cardiac disease analysis Mouse heart atria were dissected for RNA extraction and hybridisation on...
ORGANISM(S): Mus musculus 
2010-04-07 | E-GEOD-12420 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of soleus muscle from lean and obese Zucker rats following exercise training
Endurance exercise training has been shown to decrease whole-body and skeletal muscle insulin resistance and increase glucose tolerance in conditions of both pre-diabetes and overt type 2 diabetes. However, the adaptive responses in skeletal muscle at the molecular and genetic level for these benef...
ORGANISM(S): Rattus norvegicus 
2009-11-16 | E-TABM-213 | biostudies-arrayexpress
TranscriptomicsHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Acute phase proteins (APPs) are an evolutionarily conserved family of proteins produced mainly in the liver in response to infection and inflammation. Despite vast pro- and anti-inflammatory properties ascribed to individual APPs, their collective function during infections remains poorly defined. U...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-22009 | biostudies-arrayexpress
UnknownEvasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.
Not available
S-EPMC5524640 | biostudies-literature
TranscriptomicsResveratrol prevents diet-induced arterial degeneration and stiffening in nonhuman primates
Cardiovascular (CV) disease is a leading cause of morbidity and mortality in Western societies. Even after accounting for traditional CV risk factors (e.g. obesity, smoking and hypertension), the inflammation-driven thickening and stiffening of central arteries is a strong predictor of adverse outco...
ORGANISM(S): Macaca mulatta 
2014-07-21 | E-GEOD-45927 | biostudies-arrayexpress
UnknownAzithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC7884931 | biostudies-literature
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