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ProteomicsThe effect of polyethylene glycol 20,000 on protein extraction efficiency of formalin-fixed, paraffin-embedded tissues
The optimal conditions and procedures for efficient and reproducible protein extraction of FFPE tissues have not yet been standardised and new sensitive techniques are continually being developed and improved upon. To our knowledge, there is no general agreement as to the choice of detergent or buff...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD014419 | Pride
Archival tissue Protein extraction 000 Peg-20 Sp3-on-bead-digestion Ffpe proteomics Mass spectrometry 
ProteomicsEvaluation of protein purification techniques and effects of storage duration on LC-MS/MS analysis of archived FFPE human CRC tissues
To elucidate cancer pathogenesis and its mechanisms at the molecular level, the collecting and characterisation of large individual patient tissue cohorts are required. Since most pathology institutes routinely preserve biopsy tissues by standardised methods of formalin fixation and paraffin embedme...
ORGANISM(S): Homo sapiens (Human) 
2021-04-06 | PXD017198 | Pride
Human Label-free shotgun mass spectrometry Ffpe Colon cancer Protein purification Archival storage Colorectal cancer 
UnknownDesigning novel possible kinase inhibitor derivatives as therapeutics against Mycobacterium tuberculosis: An in silico study.
Not available
S-EPMC6416319 | biostudies-literature
UnknownComputational characterization of Iron metabolism in the Tsetse disease vector, Glossina morsitans: IRE stem-loops.
Not available
S-EPMC4977773 | biostudies-literature
UnknownComparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome.
Not available
S-EPMC1764476 | biostudies-literature
UnknownExploration of Scaffolds from Natural Products with Antiplasmodial Activities, Currently Registered Antimalarial Drugs and Public Malarial Screen Data.
Not available
S-EPMC6273396 | biostudies-literature
UnknownA comparative analysis of trypanosomatid SNARE proteins.
Not available
S-EPMC3979113 | biostudies-literature
UnknownTSS seq based core promoter architecture in blood feeding Tsetse fly (Glossina morsitans morsitans) vector of Trypanosomiasis.
Not available
S-EPMC4578606 | biostudies-literature
UnknownIdentification and characterization of microRNAs expressed in the African malaria vector Anopheles funestus life stages using high throughput sequencing.
Not available
S-EPMC5101901 | biostudies-literature
UnknownResistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis.
Not available
S-EPMC4745158 | biostudies-literature
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