Sort   by:  
 Page size 
Transcriptomicschromatin associated RNAs
RNA has been suggested to play a major role in the regulation of higher-order structures of chromatin. This study investigated chromatin-associated RNA (caRNA) in Drosophila melanogaster by applying high-throughput sequencing to RNA molecules that co-fractionate with chromatin. Using a cell-free in ...
ORGANISM(S): Drosophila melanogaster 
2014-06-19 | E-MTAB-1237 | biostudies-arrayexpress
ProteomicsCharacterization of chromatin associated RNA-binding proteins by SPACE
Chromatin processes such as DNA replication, transcription and RNA processing are mediated by intermolecular transactions among proteins, RNAs and the genome. Although DNA-protein and RNA-protein interactions have been studied extensively, reliable and efficient identification of chromatin-associate...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-25 | PXD023903 | Pride
Proteomics Pluripotency Idr Chromatin Dazl Rbp 
TranscriptomicsWidespread RNA Binding by Chromatin Associated Proteins
Recent evidence suggests that RNA interaction can regulate the activity and localization of DNA binding proteins, particularly chromatin-associated proteins. However, it is unknown if these observations are specialized instances for a few key RNAs and chromatin factors in specific contexts, or a gen...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-67963 | biostudies-arrayexpress
TranscriptomicsThe genomic landscape of cohesin-associated chromatin interactions
Cohesin is implicated in establishing tissue-specific DNA loops that target enhancers to promoters, and also localizes to sites bound by the insulator protein CTCF, which blocks enhancer-promoter communication. However, cohesin-associated interactions have not been characterized on a genome-wide sca...
ORGANISM(S): Mus musculus 
2013-05-22 | E-GEOD-42237 | biostudies-arrayexpress
GenomicsProteo-Genomic Characterization and Mapping of Nucleosomes Decoded by Brd and HP1 Proteins (Chip-Seq data)
Background: Histone post-translational modifications (PTMs) constitute a branch of epigenetic mechanisms that can control the expression of eukaryotic genes in a heritable manner. Recent studies have identified several PTM-binding proteins containing diverse specialized domains whose recognition of ...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-39579 | biostudies-arrayexpress
GenomicsChromatin profiling reveals novel proteins associated with histone-marked genomic regions
Our understanding of the functions of DNA elements is limited by the paucity of information about the spectrum of proteins that occupy these genomic regions. Here we describe an approach to identify proteins associated with genomic regions whose chromatin is marked by specific modified histones, whi...
ORGANISM(S): Mus musculus 
2015-02-05 | E-GEOD-62380 | biostudies-arrayexpress
TranscriptomicsArgonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq)
While Argonaute (AGO) proteins play a major role in transcriptional gene silencing (TGS) in many organisms, their role in the nucleus of somatic mammalian cells remains elusive. Here, we have purified AGO1 and AGO2 chromatin-embedded complexes, and found these proteins associated with previously des...
ORGANISM(S): Homo sapiens 
2012-09-10 | E-GEOD-39748 | biostudies-arrayexpress
ProteomicsProteins associated with chromatin in Hela cells detected by LC-MS
Chromatin fraction was seperated from Hela cells. Proteins associated with chromatin was detected by LC-MS.
ORGANISM(S): Homo sapiens (Human) 
2024-11-15 | PXD053976 | Pride
Hela chromatin lc-ms 
TranscriptomicsArgonaute proteins couple chromatin silencing to alternative splicing (exon array)
While Argonaute (AGO) proteins play a major role in transcriptional gene silencing (TGS) in many organisms, their role in the nucleus of somatic mammalian cells remains elusive. Here, we have purified AGO1 and AGO2 chromatin-embedded complexes, and found these proteins associated with previously des...
ORGANISM(S): Mus musculus 
2012-09-10 | E-GEOD-39746 | biostudies-arrayexpress
TranscriptomicsGenome-wide binding of replication initiation proteins in Bacillus subtilis
Initiation of DNA replication requires binding of the initiator protein, DnaA, to specific binding sites in the chromosomal origin of replication, oriC. In low G+C Gram-positive bacteria, the primosomal proteins DnaD and DnaB, in conjunction with loader ATPase DnaI, load the replicative helicase at ...
ORGANISM(S): Bacillus subtilis 
2010-12-07 | E-GEOD-23686 | biostudies-arrayexpress
Sort   by:  
 Page size