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MetabolomicsA metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance
Tissues are exposed to diverse inflammatory challenges that shape future inflammatory responses. While cellular metabolism regulates immune function, how metabolism programs and stabilizes immune states within tissues and tunes susceptibility to inflammation is poorly understood. Here, we describe a...
2024-10-25 | MTBLS10416 | MetaboLights
MetabolomicsLong-term low-dose ionizing radiation induced chromosome-aberration-specific metabolic phenotype changes in radiation workers

Long-term low-dose ionizing radiation (LLIR) widely exists in human life and has been confirmed to have potential pathogenic effects on cancer and cardiovascular diseases. However, it is technically and ethically unfeasible to explore LLIR-induced phenotypic changes in the human cohort, leading t...

2022-04-07 | MTBLS3854 | MetaboLights
UnknownThe Chromosome 18 Clinical Resource Center.
Not available
S-EPMC6014460 | biostudies-literature
MetabolomicsA chromosome-level genome assembly and multi-omics analyses provide insights into the biosynthesis of piperlongumine in Piper sarmentosum

Piper sarmentosum Roxb. is a significant medicinal and edible plant, and its active compound piperlongumine (PL) has garnered attention due to its pharmacological activities, including anticancer and anti-inflammatory effects. However, the key enzymes and regulatory mechanisms of its biosynt...

2025-12-17 | MTBLS13523 | MetaboLights
ProteomicsUpdate on virtual-experimental 2DE approach in chromosome-centric human proteome project
In the boundaries of chromosome-centric Human Proteome Project c-HPP to obtain information about proteoforms coded by chromosome 18, several cell lines were analyzed. In our study we have been using proteoform separation by 2DE (sectional analysis) and semi-virtual 2DE with following shotgun mass-sp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-12 | MSV000086448 | MassIVE
MetabolomicsMetabolome analysis on multi-connected biparental chromosome segment substitution line populations in rice
Not available
ORGANISM(S): Oryza sativa Japonica Group 
ST001031 | MetabolomicsWorkbench
TranscriptomicsIdentification of differentially methylated regions between placentas and maternal blood cells on chromosome 18
Comparison of DNA methylation levels of chromosome 18 between placentas and blood cells of pregnant women Extracted DNA from 5 cases of placental tissues and 5 cases of maternal blood cell was subjected to MeDIP (methylated DNA immunoprecipitation) and hybridized to Affymetrix GeneChip® Human Tiling...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-22837 | biostudies-arrayexpress
ProteomicsThe human proteome project, C-HPP 18 chromosome project
The Russian part of C-HPP is aimed to identify proteins encoded by the 18 human chromosome. In this project, 3 liver tissue samples were studied by standart SRM and 2 dimensional liquid chromatography approach to enhance the sensitivity of the MS method. The total amount of proteins found in samples...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD028510 | Pride
Srm Ups1 Chromosome 18 Liver Mrm C-hpp 18 
TranscriptomicsGlobal gene transcription analysis in response to changes in chromosome supercoiling in Streptomyces coelicolor
We address the transcriptional response to both novobiocin-induced rapid chromosome relaxation or long-term topological imbalance, both increased and decreased supercoiling, in environmental antibiotic-producing bacteria belonging to the Streptomyces genus.
ORGANISM(S): Streptomyces coelicolor A3(2) 
2019-06-22 | E-MTAB-8071 | biostudies-arrayexpress
ProteomicsUpdate on virtual-experimental 2DE approach in chromosome-centric human proteome project
In the boundaries of chromosome-centric Human Proteome Project c-HPP to obtain information about proteoforms coded by chromosome 18, several cell lines were analyzed. In our study we have been using proteoform separation by 2DE (sectional analysis) and semi-virtual 2DE with following shotgun mass-sp...
ORGANISM(S): Homo sapiens (Human) 
2018-09-24 | PXD010142 | Pride
Esi lc-ms/ms Inventory Proteoforms Mass spectrometry Chromosome 18 Chromosome-centric Two-dimensional electrophoresis Proteome 
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