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ProteomicsWnt signaling recruits KIF2A to the spindle to ensure chromosome congression during mitosis
Canonical Wnt signaling plays critical roles in development and tissue renewal by regulating β-catenin target genes. Recent evidence showed that β-catenin-independent Wnt signaling is also required for faithful execution of mitosis. This mitotic Wnt signaling functions through Wnt-dependent stabiliz...
ORGANISM(S): Homo sapiens (Human) 
2021-11-17 | PXD022724 | Pride
Stem cell Kif2a Wnt/stop Kinesin-13 Mitosis Dishevelled Wnt signaling Plk1 Chromosome congression 
TranscriptomicsBeclin-1 is dispensable for chromosome congression and proper outer kinetochore assembly
Chromosomal instability (CIN) is defined by the propensity to acquire structural and/or numerical aberration in the normal cellular karyotype and is often associated with cancer. Autophagy is a catabolic process that leads to the recycling of cellular components that may positively or negatively imp...
ORGANISM(S): Homo sapiens 
2015-09-02 | E-GEOD-69052 | biostudies-arrayexpress
ProteomicsA SUMO-Dependent Protein Network Regulates Chromosome Congression During Oocyte Meiosis
During Caenorhabditis elegans oocyte meiosis, a multi-protein complex localised between homologous chromosomes, the ring complex (RC), promotes chromosome congression through the action of the chromokinesin KLP-19. While some RC components are known, the mechanism of RC assembly has remained obscure...
ORGANISM(S): Caenorhabditis elegans 
2020-10-15 | PXD005202 | Pride
Klp-19 Pias C. elegans Sumoylation sites 
UnknownChromosome congression in the absence of kinetochore fibres.
Not available
S-EPMC2895821 | biostudies-literature
UnknownKinesin-5 mediated chromosome congression in insect spindles.
Not available
S-EPMC5849273 | biostudies-literature
UnknownThe CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity.
Not available
S-EPMC2140114 | biostudies-literature
UnknownBUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression.
Not available
S-EPMC3654266 | biostudies-literature
UnknownCENP-E initiates chromosome congression by opposing Aurora kinases to promote end-on attachments.
Not available
S-EPMC12540835 | biostudies-literature
UnknownKinetochore-centrosome feedback linking CENP-E and Aurora kinases controls chromosome congression.
Not available
S-EPMC12540731 | biostudies-literature
UnknownThe microtubule plus-end tracking protein Bik1 is required for chromosome congression.
Not available
S-EPMC9282014 | biostudies-literature
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