Sort   by:  
 Page size 
TranscriptomicsChromophobe and Oncocytoma Renal Cell Carcinomas: gene expression and SNP analysis
Chromosomal abnormalities, such as structural and numerical abnormalities, are a common occurrence in cancer. The close association of homologous chromosomes during interphase, a phenomenon termed somatic chromosome pairing, has been observed in cancerous cells, but the functional consequences of so...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-8271 | biostudies-arrayexpress
ProteomicsIn vitro phosphorylation of ASY1 by CDKA;1
Meiosis is a complex cell division program reducing chromosome number as a prerequisite for sexual reproduction and at the same time leading to a new combination of parental alleles contributing to biodiversity. Little is known about how the distinct order of the molecular processes of meiosis are o...
ORGANISM(S): Arabidopsis Thaliana 
PXD011335 | panorama
GenomicsX-chromosome dynamics revealed by the RNA interactome and chromosomal binding of CTCF
CTCF is a master regulator that plays a role in genome architecture and gene expression. A key aspect of CTCF’s mechanism involves bringing together distant genetic elements for intra- and inter-chromosomal interactions. Evidence from epigenetic processes, such as X-chromosome inactivation (XCI), su...
ORGANISM(S): Mus musculus 
2015-01-09 | E-GEOD-58242 | biostudies-arrayexpress
GenomicsDeterminants of chromosome organization: Loop extrusion or boundary:boundary pairing?
Determinants of chromosome organization: Loop extrusion or boundary:boundary pairing?
PRJNA924678 | ENA
TranscriptomicsSYCP2 recruits HORMAD2 for chromosome-axis-associated ATR signaling, unsynapsed chromatin silencing, and synapsis surveillance in meiosis
Meiotic progression in mammals is governed by tightly coordinated transcriptional programs and surveillance mechanisms that ensure the successful pairing, synapsis, and segregation of homologous chromosomes. In spermatocytes, homolog pairing is safeguarded by the pachytene checkpoint, whose mechanis...
ORGANISM(S): Mus musculus 
2026-06-18 | E-MTAB-16317 | biostudies-arrayexpress
GenomicsThe genome-wide, multi-layered architecture of chromosome pairing in early Drosophila embryos
The genome-wide, multi-layered architecture of chromosome pairing in early Drosophila embryos
PRJNA496493 | ENA
OtherPAR-TERRA RNA directs homologous sex chromosome pairing
In mammals, homologous chromosomes rarely pair outside meiosis. One exception is the X chromosome, which transiently pairs during X-chromosome inactivation (XCI). How two chromosomes find each other in 3D space is not known. Here, we reveal a required interaction between the X-inactivation center (X...
ORGANISM(S): Mus musculus 
2017-07-10 | GSE69887 | GEO
ProteomicsDistinct intersecting pathways link homolog pairing to initiation of meiotic chromosome synapsis
Faithful meiotic segregation requires pairwise alignment of the homologous chromosomes and Synaptonemal Complex assembly (SC) at their interface. Here, we investigate on new factors that promote and coordinate these events during C. elegans meiosis. We identify BRA-2 (BMP Receptor Associated family ...
ORGANISM(S): Caenorhabditis elegans 
2025-03-14 | PXD053401 | Pride
Caenorhabditis elegans Bra-2 Him-17 Lc-ms/ms 
GenomicsChromosome structure in Drosophila is determined by boundary pairing not loop extrusion
Chromosome structure in Drosophila is determined by boundary pairing not loop extrusion
PRJNA1096317 | ENA
UnknownPAR-TERRA directs homologous sex chromosome pairing.
Not available
S-EPMC5553554 | biostudies-literature
Sort   by:  
 Page size