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ProteomicsProteomics of muscle chronological ageing in post-menopausal women
Background Muscle ageing contributes to both loss of functional autonomy and increased morbidity. Muscle atrophy accelerates after 50 years of age, but the mechanisms involved are complex and likely result from the alteration of a variety of interrelated functions. In order to better understand the ...
ORGANISM(S): Homo sapiens (Human) 
2015-02-19 | PXD001527 | Pride
Human Sarcopenia Skeletal muscle Proteomics Ageing Biomarkers 
OtherProteomics of muscle chronological ageing in post-menopausal women.
Data from ProteomeXchange, PXD ID: PXD001527. File: E-PP-proteolyse-682(1179).mgf Published as part of BMC Genomics. 2014 15:1165 . From the Abstract: {{i}} Muscle samples were compared between adult (56 years) and old (78 years) post-menopausal women. In addition to total muscle extracts, low-ioni...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32310006844 | GPMDB
Resource Reanalysis 
TranscriptomicsTranscription profiling of S. cerevisiae (budding yeast) mutants reveals Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and programmed cell death
Changes in the transcriptome of Isc1p deficient mutants. The inositolphosphosphingolipid phospholipase C (Isc1p) of Saccharomyces cerevisiae belongs to the family of neutral sphingomyelinases that generates the bioactive sphingolipid ceramide. In this work the role of Isc1p in oxidative stress resis...
ORGANISM(S): Saccharomyces cerevisiae 
2008-02-05 | E-MEXP-1136 | biostudies-arrayexpress
TranscriptomicsFunctional Comparison of Chronological and In Vitro Aging: Differential Role of the Cytoskeleton and Mitochondria in Mesenchymal Stromal Cells
Mesenchymal stromal cells (MSCs) are of high relevance for the regeneration of mesenchymal tissues such as bone and cartilage. The promising role of MSCs in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age, t...
ORGANISM(S): Rattus norvegicus 
2013-01-05 | E-GEOD-36596 | biostudies-arrayexpress
UnknownBarcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast.
Not available
S-EPMC8246024 | biostudies-literature
UnknownScreening of selected ageing-related proteins that extend chronological life span in yeast Saccharomyces cerevisiae.
Not available
S-EPMC8683414 | biostudies-literature
UnknownProteomics of muscle chronological ageing in post-menopausal women.
Not available
S-EPMC4523020 | biostudies-literature
ProteomicsRemodeling of the cardiac extracellular matrix proteome during chronological and pathological aging
Impaired extracellular matrix (ECM) remodeling is a hallmark of many chronic inflammatory disorders that can lead to cellular dysfunction, aging, and disease progression. The ECM of the aged heart and its effects on cardiac cells during chronological and pathological aging are relatively poorly unde...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-08 | PXD040234 | Pride
Hutchinson-gilford progeria syndrome Proteomics Left ventricle Lactadherin Extracellular matrix Aging 
ProteomicsRemodeling of the cardiac extracellular matrix proteome during chronological and pathological aging
Impaired extracellular matrix (ECM) remodeling is a hallmark of many chronic inflammatory disorders that can lead to cellular dysfunction, aging, and disease progression. The ECM of the aged heart and its effects on cardiac cells during chronological and pathological aging are poorly understood acro...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2024-01-08 | PXD039548 | Pride
Hutchinson-gilford progeria syndrome Proteomics Left ventricle Lactadherin Extracellular matrix Aging 
UnknownSex and education differences in trajectories of physiological ageing: longitudinal analysis of a prospective English cohort study.
Not available
S-EPMC11954548 | biostudies-literature
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