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MetabolomicsTargeted polyamine metabolomics of ATP13A4-deficient cellular and mouse models

ATP13A4 is a polyamine transporter enriched in astrocytes that regulates extracellular polyamine homeostasis. This study contains targeted LC-MS/MS metabolomics data from ATP13A4-deficient cellular and mouse models, including C8-D1A astrocytic cells, astrocyte-conditioned medium, mouse cortex, pl...

2026-06-10 | MTBLS14724 | MetaboLights
TranscriptomicsDynamics of intercellular and extracellular (exosomal) miRNAs in hypoxic RPMI8226 cells
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45388 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and extracellular (exosomal) miRNAs in hypoxic SUDHL4 cells
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45387 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and extracellular (exosomal) miRNAs in hypoxic K562 cells
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45289 | biostudies-arrayexpress
ProteomicsDevelopment of an optimized LC-MS workflow for Host Cell Protein characterization to support upstream process development
Host cell proteins (HCPs) co-expressed during the production of biotherapeutics can affect the safety, efficacy and stability of the final product. As such, monitoring HCPs populations and amounts throughout the production and purification process are an essential part of the overall quality control...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2025-05-07 | PXD053035 | Pride
Process analytical technologies Host cell proteins Lc-ms Clarified cell culture fluid Absolute quantification Chinese hamster ovary Data-independent acquisition Hi3 quantification Bio-processing 
UnknownImpact of stirred suspension bioreactor culture on the differentiation of murine embryonic stem cells into cardiomyocytes.
Not available
S-EPMC3260255 | biostudies-literature
UnknownExpression and function of an S1-type nuclease in the digestive fluid of a sundew, Drosera adelae.
Not available
S-EPMC9992940 | biostudies-literature
TranscriptomicsGene expression in cell cycle of Cyanidioschyzon merolae_1
To analyze mitotic cycle and organelle proliferation cycle, we investigated C.merolae cells across two cell cycles synchronized by light and dark cycles. C.merolae has one nucleus, mitochondria and chloroplast (Kuroiwa et al,1993. Protoplasma). Their division are strictly regulated by cell cycle and...
ORGANISM(S): Cyanidioschyzon merolae 
2010-05-19 | E-GEOD-8268 | biostudies-arrayexpress
TranscriptomicsTrancription profiling of the hepatoma cell line Huh7 infected with the Hepatitis C Virus
Hepatitis C Virus is a leading cause of chronic liver disease. The identification and characterisation of key host cellular factors that play a role in the HCV replication cycle is important for the understanding of disease pathogenesis and the identification of novel anti-viral therapeutic targets....
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-20948 | biostudies-arrayexpress
TranscriptomicsTranscription profile of T. thermophilus HB8 strain lacking mutS, mutL, or mutS2 gene
We analyzed the expression profile of mutS, mutL, or mutS2 deletion mutant strain of Thermus thermophils HB8 during the exponential growth phase. When compared with wild type using t-test (P < 0.01), 8, 111, and 18 genes were over 2-fold up-regulated in mutS, mutL, and mutS2-lacking strains, respec...
ORGANISM(S): Thermus thermophilus HB8 
2011-06-02 | E-GEOD-22567 | biostudies-arrayexpress
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